Southwest® flights from Midland/Odessa to Myrtle Beach from $279

Promo Code

Low fares from Midland/Odessa to Myrtle Beach

$

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 05/10/2026

One-way

Basic

From
$279
Seen: 10 hrs ago

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 05/10/2026

One-way

Choice

From
$319
Seen: 10 hrs ago

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 05/10/2026

One-way

Choice Preferred

From
$399
Seen: 10 hrs ago

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 05/10/2026

One-way

Choice Extra

From
$459
Seen: 10 hrs ago

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 02/28/2026

One-way

Choice

From
$524
Seen: 2 hrs ago

Midland/Odessa (MAF)to

Myrtle Beach (MYR)
Depart: 02/28/2026

One-way

Choice Preferred

From
$604
Seen: 2 hrs ago

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Explore flights from Midland/Odessa to Myrtle Beach

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Midland International Airport
Arriving at:
Myrtle Beach International Airport
Distance:
1357 miles

Route Information

35† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 35 weekly flights from Midland/Odessa to Myrtle Beach on Southwest Airlines.
To find the lowest fares by day and time to fly Midland/Odessa to Myrtle Beach with Southwest, check out our Low Fare Calendar.
You can rent a car at Myrtle Beach International Airport book yours with your flight.
Yes! Flights from Midland/Odessa to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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