Looking for more low-fare flights?
Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.
Find low faresSouthwest® flights from Milwaukee to Buffalo/Niagara Falls from $159
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Low fares from Milwaukee to Buffalo/Niagara Falls
$
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 05/11/2026
One-way
Basic
From
$144
Seen: 23 hrs ago
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 03/05/2026
One-way
Basic
From
$159
Seen: 16 hrs ago
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 03/12/2026
One-way
Basic
From
$169
Seen: 11 hrs ago
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 05/11/2026
One-way
Choice
From
$174
Seen: 23 hrs ago
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 04/16/2026
One-way
Basic
From
$179
Seen: 20 hrs ago
Milwaukee (MKE)to
Buffalo/Niagara Falls (BUF)
Depart: 04/17/2026
One-way
Basic
From
$179
Seen: 20 hrs ago
Explore flights from Milwaukee to Buffalo/Niagara Falls
location_on
location_on
Flight Details
Departing from:
General Mitchell Airport
Arriving at:
Buffalo Niagara International Airport
Distance:
465 miles
Route Information
67† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 67 weekly flights from Milwaukee to Buffalo/Niagara Falls on Southwest Airlines.
To find the lowest fares by day and time to fly Milwaukee to Buffalo/Niagara Falls with Southwest, check out our Low Fare Calendar.
You can rent a car at Buffalo Niagara International Airport book yours with your flight.
Yes! Flights from Milwaukee to Buffalo/Niagara Falls—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.