Southwest® flights from New York (LaGuardia) to Knoxville from $194

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Low fares from New York (LaGuardia) to Knoxville

$

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 11/12/2026

One-way

Basic

From
$165

Low fares from New York (LaGuardia) to Knoxville

$

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 09/03/2026

One-way

Basic

From
$194
Seen: 5 hrs ago

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 08/20/2026

One-way

Basic

From
$224
Seen: 15 hrs ago

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 10/16/2026

One-way

Basic

From
$229
Seen: 8 hrs ago

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 09/03/2026

One-way

Choice

From
$234
Seen: 5 hrs ago

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 09/20/2026

One-way

Basic

From
$234
Seen: 1 hour ago

New York (LaGuardia) (LGA)to

Knoxville (TYS)
Depart: 08/20/2026

One-way

Choice

From
$264
Seen: 15 hrs ago

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Explore flights from New York (LaGuardia) to Knoxville

Aug 2026
From$224*
Seen: 15 hrs ago
One Way/Basic
Sep 2026
From$194*
Seen: 5 hrs ago
One Way/Basic
Oct 2026
From$229*
Seen: 8 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $224
Displaying fares for August-2026
  • LGA–TYS, 08/03/2026: From $375
    03

    Mon

    AUG

  • LGA–TYS, 08/04/2026: From $370
    04

    Tue

  • LGA–TYS, 08/05/2026: From $370
    05

    Wed

  • LGA–TYS, 08/06/2026: From $370
    06

    Thu

  • LGA–TYS: cmp-view-offers-disclaimer. Find Offers
    07

    Fri

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    08

    Sat

  • LGA–TYS, 08/09/2026: From $344
    09

    Sun

  • LGA–TYS, 08/10/2026: From $339
    10

    Mon

  • LGA–TYS, 08/11/2026: From $339
    11

    Tue

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    12

    Wed

  • LGA–TYS: cmp-view-offers-disclaimer. Find Offers
    13

    Thu

  • LGA–TYS, 08/14/2026: From $339
    14

    Fri

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    15

    Sat

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    16

    Sun

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    17

    Mon

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    18

    Tue

  • LGA–TYS: cmp-view-offers-disclaimer. Find Offers
    19

    Wed

  • LGA–TYS, 08/20/2026: From $224
    20

    Thu

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    21

    Fri

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    22

    Sat

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    23

    Sun

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    24

    Mon

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    25

    Tue

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    26

    Wed

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    27

    Thu

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    28

    Fri

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    29

    Sat

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    30

    Sun

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    31

    Mon

  • LGA–TYS: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    SEP

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    02

    Wed

    • Range$224-$375

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    La Guardia Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    647 miles

    Route Information

    38† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 38 weekly flights from New York (LaGuardia) to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly New York (LaGuardia) to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from New York (LaGuardia) to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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