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Find low faresSouthwest® flights from Orange County/Santa Ana to Columbus from $169
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Low fares from Orange County/Santa Ana to Columbus
$
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 03/04/2026
One-way
Basic
From
$169
Seen: 22 hrs ago
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 03/05/2026
One-way
Basic
From
$190
Seen: 7 hrs ago
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 04/16/2026
One-way
Basic
From
$193
Seen: 22 hrs ago
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 04/01/2026
One-way
Basic
From
$193
Seen: 3 hrs ago
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 04/18/2026
One-way
Basic
From
$198
Seen: 12 hrs ago
Orange County/Santa Ana (SNA)to
Columbus (CMH)
Depart: 03/04/2026
One-way
Choice
From
$209
Seen: 22 hrs ago
Explore flights from Orange County/Santa Ana to Columbus
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Flight Details
Departing from:
John Wayne Airport
Arriving at:
Port Columbus International Airport
Distance:
1974 miles
Route Information
112† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 112 weekly flights from Orange County/Santa Ana to Columbus on Southwest Airlines.
To find the lowest fares by day and time to fly Orange County/Santa Ana to Columbus with Southwest, check out our Low Fare Calendar.
You can rent a car at Port Columbus International Airport book yours with your flight.
Yes! Flights from Orange County/Santa Ana to Columbus—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.