Southwest® flights from Orange County/Santa Ana to San Francisco from $75

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Low fares from Orange County/Santa Ana to San Francisco

$

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 01/23/2027

One-way

Basic

From
$75
Seen: 11 hrs ago

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 01/20/2027

One-way

Basic

From
$80
Seen: 1 hour ago

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 12/16/2026

One-way

Basic

From
$80
Seen: 16 hrs ago

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 02/10/2027

One-way

Basic

From
$80
Seen: 14 hrs ago

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 01/09/2027

One-way

Basic

From
$80
Seen: 10 hrs ago

Orange County/Santa Ana (SNA)to

San Francisco (SFO)
Depart: 02/09/2027

One-way

Basic

From
$80
Seen: 12 hrs ago
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Explore flights from Orange County/Santa Ana to San Francisco

cmp-daily-histogram-bars-legend-min-price-aria-label $100
cmp-daily-histogram-bars-legend-max-price-aria-label $414
Displaying fares for November-2026
  • SNA–SFO, 11/12/2026: From $414
    12

    Thu

    NOV

  • SNA–SFO, 11/13/2026: From $414
    13

    Fri

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • SNA–SFO, 11/15/2026: From $414
    15

    Sun

  • SNA–SFO, 11/16/2026: From $414
    16

    Mon

  • SNA–SFO, 11/17/2026: From $414
    17

    Tue

  • SNA–SFO, 11/18/2026: From $180
    18

    Wed

  • SNA–SFO, 11/19/2026: From $305
    19

    Thu

  • SNA–SFO, 11/20/2026: From $305
    20

    Fri

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • SNA–SFO, 11/23/2026: From $289
    23

    Mon

  • SNA–SFO, 11/24/2026: From $289
    24

    Tue

  • SNA–SFO, 11/25/2026: From $225
    25

    Wed

  • SNA–SFO, 11/26/2026: From $225
    26

    Thu

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • SNA–SFO, 11/28/2026: From $329
    28

    Sat

  • SNA–SFO, 11/29/2026: From $310
    29

    Sun

  • SNA–SFO, 11/30/2026: From $225
    30

    Mon

  • SNA–SFO, 12/01/2026: From $159
    01

    Tue

    DEC

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • SNA–SFO, 12/04/2026: From $114
    04

    Fri

  • SNA–SFO: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • SNA–SFO, 12/06/2026: From $159
    06

    Sun

  • SNA–SFO, 12/07/2026: From $114
    07

    Mon

  • SNA–SFO, 12/08/2026: From $100
    08

    Tue

  • SNA–SFO, 12/09/2026: From $100
    09

    Wed

  • SNA–SFO, 12/10/2026: From $114
    10

    Thu

  • SNA–SFO, 12/11/2026: From $100
    11

    Fri

  • Range$100-$414

    Flight Details

    Departing from:
    John Wayne Airport
    Arriving at:
    San Francisco International Airport
    Distance:
    372 miles

    Questions we hear the most

    There are 129 weekly flights from Orange County/Santa Ana to San Francisco on Southwest Airlines.
    To find the lowest fares by day and time to fly Orange County/Santa Ana to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from Orange County/Santa Ana to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Popular Flights from Orange County/Santa Ana