Southwest® flights from Orange County/Santa Ana to St. Louis from $171

Promo Code

Low fares from Orange County/Santa Ana to St. Louis

$

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/03/2026

One-way

Basic

From
$171
Seen: 22 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 01/27/2027

One-way

Basic

From
$171
Seen: 19 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 11/25/2026

One-way

Basic

From
$208
Seen: 18 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 01/26/2027

One-way

Basic

From
$208
Seen: 18 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 11/17/2026

One-way

Basic

From
$208
Seen: 17 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 11/14/2026

One-way

Basic

From
$208
Seen: 13 hrs ago

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Explore flights from Orange County/Santa Ana to St. Louis

Oct 2026
From$624*
Seen: 8 hrs ago
One Way/Basic
Nov 2026
From$208*
Seen: 6 hrs ago
One Way/Basic
Dec 2026
From$171*
Seen: 22 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $208
cmp-daily-histogram-bars-legend-max-price-aria-label $624
Displaying fares for October-2026
  • SNA–STL, 10/25/2026: From $624
    25

    Sun

    OCT

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • SNA–STL, 10/28/2026: From $624
    28

    Wed

  • SNA–STL, 10/29/2026: From $624
    29

    Thu

  • SNA–STL, 10/30/2026: From $624
    30

    Fri

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • SNA–STL, 11/01/2026: From $534
    01

    Sun

    NOV

  • SNA–STL, 11/02/2026: From $534
    02

    Mon

  • SNA–STL, 11/03/2026: From $534
    03

    Tue

  • SNA–STL, 11/04/2026: From $534
    04

    Wed

  • SNA–STL, 11/05/2026: From $534
    05

    Thu

  • SNA–STL, 11/06/2026: From $534
    06

    Fri

  • SNA–STL, 11/07/2026: From $314
    07

    Sat

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

  • SNA–STL, 11/10/2026: From $314
    10

    Tue

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    12

    Thu

  • SNA–STL, 11/13/2026: From $314
    13

    Fri

  • SNA–STL, 11/14/2026: From $208
    14

    Sat

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • SNA–STL, 11/16/2026: From $247
    16

    Mon

  • SNA–STL, 11/17/2026: From $208
    17

    Tue

  • SNA–STL, 11/18/2026: From $208
    18

    Wed

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • SNA–STL, 11/21/2026: From $208
    21

    Sat

  • SNA–STL, 11/22/2026: From $247
    22

    Sun

  • SNA–STL, 11/23/2026: From $208
    23

    Mon

  • SNA–STL, 11/24/2026: From $208
    24

    Tue

    • Range$208-$624

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    John Wayne Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    1569 miles

    Questions we hear the most

    There are 148 weekly flights from Orange County/Santa Ana to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Orange County/Santa Ana to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Orange County/Santa Ana to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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