Southwest® flights from Orange County/Santa Ana to St. Louis from $217

Promo Code

Low fares from Orange County/Santa Ana to St. Louis

$

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$217
Seen: 19 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/22/2026

One-way

Basic

From
$217
Seen: 10 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/24/2026

One-way

Basic

From
$237
Seen: 15 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 02/11/2027

One-way

Basic

From
$237
Seen: 44 minutes ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/19/2026

One-way

Basic

From
$237
Seen: 8 hrs ago

Orange County/Santa Ana (SNA)to

St. Louis (STL)
Depart: 12/12/2026

One-way

Basic

From
$237
Seen: 8 hrs ago

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Explore flights from Orange County/Santa Ana to St. Louis

Nov 2026
From$354*
Seen: 2 hrs ago
One Way/Basic
Dec 2026
From$217*
Seen: 19 hrs ago
One Way/Basic
Jan 2027
From$279*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $237
cmp-daily-histogram-bars-legend-max-price-aria-label $634
Displaying fares for November-2026
  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

    NOV

  • SNA–STL, 11/16/2026: From $634
    16

    Mon

  • SNA–STL, 11/17/2026: From $634
    17

    Tue

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • SNA–STL, 11/19/2026: From $634
    19

    Thu

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • SNA–STL, 11/25/2026: From $544
    25

    Wed

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • SNA–STL, 11/28/2026: From $354
    28

    Sat

  • SNA–STL, 11/29/2026: From $354
    29

    Sun

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • SNA–STL, 12/04/2026: From $257
    04

    Fri

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • SNA–STL, 12/11/2026: From $257
    11

    Fri

  • SNA–STL, 12/12/2026: From $237
    12

    Sat

  • SNA–STL, 12/13/2026: From $290
    13

    Sun

  • SNA–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

    • Range$237-$634

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    John Wayne Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    1569 miles

    Questions we hear the most

    There are 148 weekly flights from Orange County/Santa Ana to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Orange County/Santa Ana to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Orange County/Santa Ana to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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