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Find low faresSouthwest® flights from San Diego to Charleston from $141
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1 Passenger
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Low fares from San Diego to Charleston
$
San Diego (SAN)to
Charleston (CHS)
Depart: 04/14/2026
One-way
Basic
From
$141
Seen: 17 minutes ago
San Diego (SAN)to
Charleston (CHS)
Depart: 03/24/2026
One-way
Basic
From
$141
Seen: 1 hour ago
San Diego (SAN)to
Charleston (CHS)
Depart: 03/25/2026
One-way
Basic
From
$146
Seen: 6 hrs ago
San Diego (SAN)to
Charleston (CHS)
Depart: 03/12/2026
One-way
Basic
From
$169
Seen: 19 hrs ago
San Diego (SAN)to
Charleston (CHS)
Depart: 02/25/2026
One-way
Basic
From
$169
Seen: 21 hrs ago
San Diego (SAN)to
Charleston (CHS)
Depart: 03/06/2026
One-way
Basic
From
$172
Seen: 23 hrs ago
Explore flights from San Diego to Charleston
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Flight Details
Departing from:
San Diego International Airport
Arriving at:
Charleston International Airport
Distance:
2150 miles
Route Information
82† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 82 weekly flights from San Diego to Charleston on Southwest Airlines.
To find the lowest fares by day and time to fly San Diego to Charleston with Southwest, check out our Low Fare Calendar.
You can rent a car at Charleston International Airport book yours with your flight.
Yes! Flights from San Diego to Charleston—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.