Southwest® flights from Seattle/Tacoma to Des Moines from $131

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Low fares from Seattle/Tacoma to Des Moines

$

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 11/17/2026

One-way

Basic

From
$131
Seen: 19 hrs ago

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 11/18/2026

One-way

Basic

From
$131
Seen: 20 hrs ago

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 11/10/2026

One-way

Basic

From
$131
Seen: 13 hrs ago

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 11/19/2026

One-way

Basic

From
$136
Seen: 21 hrs ago

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 12/25/2026

One-way

Basic

From
$161
Seen: 23 hrs ago

Seattle/Tacoma (SEA)to

Des Moines (DSM)
Depart: 11/18/2026

One-way

Choice

From
$177
Seen: 20 hrs ago

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Explore flights from Seattle/Tacoma to Des Moines

Oct 2026
From$289*
Seen: 5 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $131
cmp-daily-histogram-bars-legend-max-price-aria-label $440
Displaying fares for October-2026
  • SEA–DSM, 10/22/2026: From $369
    22

    Thu

    OCT

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • SEA–DSM, 10/24/2026: From $289
    24

    Sat

  • SEA–DSM, 10/25/2026: From $369
    25

    Sun

  • SEA–DSM, 10/26/2026: From $440
    26

    Mon

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • SEA–DSM, 10/28/2026: From $289
    28

    Wed

  • SEA–DSM, 10/29/2026: From $369
    29

    Thu

  • SEA–DSM, 10/30/2026: From $369
    30

    Fri

  • SEA–DSM, 10/31/2026: From $289
    31

    Sat

  • SEA–DSM, 11/01/2026: From $374
    01

    Sun

    NOV

  • SEA–DSM, 11/02/2026: From $369
    02

    Mon

  • SEA–DSM, 11/03/2026: From $294
    03

    Tue

  • SEA–DSM, 11/04/2026: From $289
    04

    Wed

  • SEA–DSM, 11/05/2026: From $309
    05

    Thu

  • SEA–DSM, 11/06/2026: From $309
    06

    Fri

  • SEA–DSM, 11/07/2026: From $289
    07

    Sat

  • SEA–DSM, 11/08/2026: From $309
    08

    Sun

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

  • SEA–DSM, 11/10/2026: From $131
    10

    Tue

  • SEA–DSM, 11/11/2026: From $259
    11

    Wed

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    12

    Thu

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • SEA–DSM, 11/15/2026: From $259
    15

    Sun

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • SEA–DSM, 11/17/2026: From $131
    17

    Tue

  • SEA–DSM, 11/18/2026: From $131
    18

    Wed

  • SEA–DSM, 11/19/2026: From $136
    19

    Thu

  • SEA–DSM, 11/20/2026: From $196
    20

    Fri

  • SEA–DSM: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

    • Range$131-$440

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Seattle/Tacoma International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    1465 miles

    Questions we hear the most

    There are 55 weekly flights from Seattle/Tacoma to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Seattle/Tacoma to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Seattle/Tacoma to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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