Southwest® flights from Tampa to Greenville-Spartanburg from $156

Promo Code

Low fares from Tampa to Greenville-Spartanburg

$

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 05/13/2026

One-way

Basic

From
$136
Seen: 17 hrs ago

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 04/13/2026

One-way

Basic

From
$156
Seen: 3 hrs ago

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 03/06/2026

One-way

Basic

From
$164
Seen: 15 hrs ago

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 03/09/2026

One-way

Basic

From
$164
Seen: 23 hrs ago

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 03/10/2026

One-way

Basic

From
$164
Seen: 22 hrs ago

Tampa (TPA)to

Greenville-Spartanburg (GSP)
Depart: 03/18/2026

One-way

Basic

From
$164
Seen: 20 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Tampa to Greenville-Spartanburg

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Tampa International Airport
Arriving at:
Greenville-Spartanburg International Airport
Distance:
477 miles

Route Information

59† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 59 weekly flights from Tampa to Greenville-Spartanburg on Southwest Airlines.
To find the lowest fares by day and time to fly Tampa to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
Yes! Flights from Tampa to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

Explore Flights from Other Popular Origins

Popular Flights from Tampa