Southwest® flights from Washington D.C. Reagan National to Knoxville from $144

Promo Code

Low fares from Washington D.C. Reagan National to Knoxville

$

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 01/28/2027

One-way

Basic

From
$114

Low fares from Washington D.C. Reagan National to Knoxville

$

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/04/2026

One-way

Basic

From
$144
Seen: 2 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/04/2026

One-way

Choice

From
$179
Seen: 2 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 10/21/2026

One-way

Basic

From
$179
Seen: 5 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 10/24/2026

One-way

Basic

From
$183
Seen: 1 hour ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Basic

From
$204
Seen: 11 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/01/2026

One-way

Basic

From
$204
Seen: 1 hour ago

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Explore flights from Washington D.C. Reagan National to Knoxville

Sep 2026
From$237*
Seen: 9 hrs ago
One Way/Basic
Oct 2026
From$179*
Seen: 5 hrs ago
One Way/Basic
Nov 2026
From$204*
Seen: 11 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $237
cmp-daily-histogram-bars-legend-max-price-aria-label $509
Displaying fares for September-2026
  • DCA–TYS, 09/21/2026: From $260
    21

    Mon

    SEP

  • DCA–TYS, 09/22/2026: From $237
    22

    Tue

  • DCA–TYS, 09/23/2026: From $237
    23

    Wed

  • DCA–TYS, 09/24/2026: From $318
    24

    Thu

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    25

    Fri

  • DCA–TYS, 09/26/2026: From $242
    26

    Sat

  • DCA–TYS, 09/27/2026: From $255
    27

    Sun

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    28

    Mon

  • DCA–TYS: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

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    30

    Wed

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    01

    Thu

    OCT

  • DCA–TYS, 10/02/2026: From $284
    02

    Fri

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    03

    Sat

  • DCA–TYS, 10/04/2026: From $237
    04

    Sun

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    05

    Mon

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    06

    Tue

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    07

    Wed

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    08

    Thu

  • DCA–TYS, 10/09/2026: From $509
    09

    Fri

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    10

    Sat

  • DCA–TYS, 10/11/2026: From $389
    11

    Sun

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    12

    Mon

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    13

    Tue

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    14

    Wed

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    15

    Thu

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    16

    Fri

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    17

    Sat

  • DCA–TYS, 10/18/2026: From $259
    18

    Sun

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    19

    Mon

  • DCA–TYS: cmp-view-offers-disclaimer. Find Offers
    20

    Tue

    • Range$237-$509

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Ronald Reagan National Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    437 miles

    Route Information

    52† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 52 weekly flights from Washington, D.C. (Reagan National) to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Washington, D.C. (Reagan National) to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Washington, D.C. (Reagan National) to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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