Southwest® flights from Washington D.C. Reagan National to Knoxville from $144

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Low fares from Washington D.C. Reagan National to Knoxville

$

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 02/19/2027

One-way

Basic

From
$114

Low fares from Washington D.C. Reagan National to Knoxville

$

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/13/2026

One-way

Basic

From
$144
Seen: 8 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/06/2026

One-way

Basic

From
$144
Seen: 16 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Basic

From
$170
Seen: 19 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 11/16/2026

One-way

Basic

From
$175
Seen: 11 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/06/2026

One-way

Choice

From
$179
Seen: 16 hrs ago

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/13/2026

One-way

Choice

From
$179
Seen: 8 hrs ago

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Explore flights from Washington D.C. Reagan National to Knoxville

Nov 2026
From$170*
Seen: 19 hrs ago
One Way/Basic
Dec 2026
From$144*
Seen: 8 hrs ago
One Way/Basic
Jan 2027
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $170
Displaying fares for November-2026
  • DCA–TYS, 11/01/2026: From $270
    01

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    NOV

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    12

    Thu

  • DCA–TYS, 11/13/2026: From $170
    13

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    14

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  • DCA–TYS, 11/16/2026: From $175
    16

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    17

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    18

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    20

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    21

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    23

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    24

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  • DCA–TYS, 11/25/2026: From $246
    25

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    26

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    27

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    28

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  • DCA–TYS, 11/29/2026: From $489
    29

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    30

    Mon

    • Range$170-$489

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Ronald Reagan National Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    437 miles

    Questions we hear the most

    There are 52 weekly flights from Washington, D.C. (Reagan National) to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Washington, D.C. (Reagan National) to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Washington, D.C. (Reagan National) to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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