Southwest® flights from Colorado Springs to Knoxville from $166

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Low fares from Colorado Springs to Knoxville

$

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 12/05/2026

One-way

Basic

From
$166

Low fares from Colorado Springs to Knoxville

$

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 12/05/2026

One-way

Basic

From
$166
Seen: 17 hrs ago

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 12/25/2026

One-way

Basic

From
$174
Seen: 2 hrs ago

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Basic

From
$174
Seen: 1 hour ago

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 12/05/2026

One-way

Choice

From
$211
Seen: 17 hrs ago

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Choice

From
$219
Seen: 1 hour ago

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 12/25/2026

One-way

Choice

From
$219
Seen: 2 hrs ago

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Explore flights from Colorado Springs to Knoxville

Oct 2026
From$247*
Seen: 18 hrs ago
One Way/Basic
Nov 2026
From$174*
Seen: 1 hour ago
One Way/Basic
Dec 2026
From$166*
Seen: 17 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $247
Displaying fares for October-2026
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  • COS–TYS, 10/23/2026: From $307
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  • COS–TYS, 10/24/2026: From $247
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  • COS–TYS, 10/25/2026: From $294
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    NOV

  • COS–TYS, 11/02/2026: From $249
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    • Range$247-$307

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    City of Colorado Springs Municipal Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    1157 miles

    Questions we hear the most

    There are 31 weekly flights from Colorado Springs to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Colorado Springs to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Colorado Springs to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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