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Find low faresSouthwest® flights from Denver to Myrtle Beach from $126
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1 Passenger
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Low fares from Denver to Myrtle Beach
$
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 03/03/2026
One-way
Basic
From
$126
Seen: 7 hrs ago
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 02/28/2026
One-way
Basic
From
$126
Seen: 8 hrs ago
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 04/25/2026
One-way
Basic
From
$135
Seen: 8 hrs ago
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 03/07/2026
One-way
Basic
From
$135
Seen: 9 hrs ago
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 03/23/2026
One-way
Basic
From
$135
Seen: 4 hrs ago
Denver (DEN)to
Myrtle Beach (MYR)
Depart: 03/09/2026
One-way
Basic
From
$135
Seen: 12 hrs ago
Explore flights from Denver to Myrtle Beach
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Flight Details
Departing from:
Denver International Airport
Arriving at:
Myrtle Beach International Airport
Distance:
1485 miles
Route Information
87† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 87 weekly flights from Denver to Myrtle Beach on Southwest Airlines.
To find the lowest fares by day and time to fly Denver to Myrtle Beach with Southwest, check out our Low Fare Calendar.
You can rent a car at Myrtle Beach International Airport book yours with your flight.
Yes! Flights from Denver to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.