Southwest® flights from Des Moines to Mexico
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1 Passenger
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Popular flight deals and low fares from Des Moines
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Des Moines (DSM)to
Cancun (CUN)Depart: 01/12/2026
From
$236
Seen: 10 hrs ago
One-way
Basic
Des Moines (DSM)to
Los Cabos (SJD)Depart: 01/17/2026
From
$307
Seen: 8 hrs ago
One-way
Basic
Des Moines (DSM)to
Puerto Vallarta (PVR)Depart: 12/26/2025
From
$950
Seen: 18 hrs ago
One-way
Choice Preferred
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
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From | To | Fare Type | Dates | Price |
|---|---|---|---|---|
| Des Moines (DSM) | Puerto Vallarta (PVR) | One-way / Basic | Depart: 02/23/2026 | From $239 Seen: 15 hrs ago |
| Des Moines (DSM) | Cancun (CUN) | One-way / Basic | Depart: 02/18/2026 | From $242 Seen: 10 hrs ago |
| Des Moines (DSM) | Los Cabos (SJD) | One-way / Basic | Depart: 03/23/2026 | From $261 Seen: 19 hrs ago |
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
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