Southwest® flights from Destin/Fort Walton Beach to Knoxville from $157

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Knoxville

Visit Knoxville


Book your flight to Knoxville and explore mountain views, live music, and nearby adventures in Gatlinburg and Pigeon Forge.

Flights available to book today. Service starts March 5, 2026.

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Low fares from Destin/Fort Walton Beach to Knoxville

$

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 05/07/2026

One-way

Basic

From
$155

Low fares from Destin/Fort Walton Beach to Knoxville

$

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 05/07/2026

One-way

Basic

From
$155
Seen: 10 minutes ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 03/07/2026

One-way

Basic

From
$157
Seen: 11 hrs ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$157
Seen: 11 hrs ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 03/09/2026

One-way

Basic

From
$157
Seen: 5 hrs ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 03/06/2026

One-way

Basic

From
$167
Seen: 11 hrs ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 05/07/2026

One-way

Choice

From
$185
Seen: 10 minutes ago

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*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

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