Southwest® flights from Houston Hobby to Knoxville from $152

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Low fares from Houston Hobby to Knoxville

$

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 10/31/2026

One-way

Basic

From
$152

Low fares from Houston Hobby to Knoxville

$

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 10/31/2026

One-way

Basic

From
$152
Seen: 19 hrs ago

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 11/02/2026

One-way

Basic

From
$152
Seen: 17 hrs ago

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 10/20/2026

One-way

Basic

From
$152
Seen: 16 hrs ago

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 11/17/2026

One-way

Basic

From
$152
Seen: 10 hrs ago

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 11/09/2026

One-way

Basic

From
$152
Seen: 12 hrs ago

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 11/11/2026

One-way

Basic

From
$152
Seen: 7 hrs ago

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Explore flights from Houston Hobby to Knoxville

Sep 2026
From$225*
Seen: 9 hrs ago
One Way/Basic
Oct 2026
From$152*
Seen: 9 hrs ago
One Way/Basic
Nov 2026
From$152*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $152
cmp-daily-histogram-bars-legend-max-price-aria-label $461
Displaying fares for September-2026
  • HOU–TYS, 09/20/2026: From $389
    20

    Sun

    SEP

  • HOU–TYS, 09/21/2026: From $285
    21

    Mon

  • HOU–TYS, 09/22/2026: From $285
    22

    Tue

  • HOU–TYS, 09/23/2026: From $285
    23

    Wed

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

  • HOU–TYS, 09/26/2026: From $225
    26

    Sat

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • HOU–TYS, 09/29/2026: From $225
    29

    Tue

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • HOU–TYS, 10/01/2026: From $304
    01

    Thu

    OCT

  • HOU–TYS, 10/02/2026: From $265
    02

    Fri

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    03

    Sat

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    04

    Sun

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    05

    Mon

  • HOU–TYS, 10/06/2026: From $190
    06

    Tue

  • HOU–TYS, 10/07/2026: From $269
    07

    Wed

  • HOU–TYS, 10/08/2026: From $461
    08

    Thu

  • HOU–TYS, 10/09/2026: From $461
    09

    Fri

  • HOU–TYS, 10/10/2026: From $419
    10

    Sat

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

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    12

    Mon

  • HOU–TYS, 10/13/2026: From $157
    13

    Tue

  • HOU–TYS, 10/14/2026: From $170
    14

    Wed

  • HOU–TYS, 10/15/2026: From $314
    15

    Thu

  • HOU–TYS, 10/16/2026: From $262
    16

    Fri

  • HOU–TYS: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

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    18

    Sun

  • HOU–TYS, 10/19/2026: From $152
    19

    Mon

    • Range$152-$461

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    William P. Hobby Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    782 miles

    Route Information

    77† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 77 weekly flights from Houston (Hobby) to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Houston (Hobby) to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Houston (Hobby) to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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