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Find low faresSouthwest® flights from Louisville to Charleston from $119
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Low fares from Louisville to Charleston
$
Louisville (SDF)to
Charleston (CHS)
Depart: 03/04/2026
One-way
Basic
From
$119
Seen: 6 hrs ago
Louisville (SDF)to
Charleston (CHS)
Depart: 02/26/2026
One-way
Basic
From
$125
Seen: 13 hrs ago
Louisville (SDF)to
Charleston (CHS)
Depart: 02/24/2026
One-way
Basic
From
$128
Seen: 3 hrs ago
Louisville (SDF)to
Charleston (CHS)
Depart: 03/04/2026
One-way
Choice
From
$149
Seen: 6 hrs ago
Louisville (SDF)to
Charleston (CHS)
Depart: 02/26/2026
One-way
Choice
From
$155
Seen: 13 hrs ago
Louisville (SDF)to
Charleston (CHS)
Depart: 02/24/2026
One-way
Choice
From
$158
Seen: 3 hrs ago
Explore flights from Louisville to Charleston
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Flight Details
Departing from:
Louisville International Airport
Arriving at:
Charleston International Airport
Distance:
485 miles
Route Information
80† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 80 weekly flights from Louisville to Charleston on Southwest Airlines.
To find the lowest fares by day and time to fly Louisville to Charleston with Southwest, check out our Low Fare Calendar.
You can rent a car at Charleston International Airport book yours with your flight.
Yes! Flights from Louisville to Charleston—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.