Southwest® flights from Manchester, NH to Knoxville from $138

Promo Code

Low fares from Manchester, NH to Knoxville

$

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 12/12/2026

One-way

Basic

From
$138

Low fares from Manchester, NH to Knoxville

$

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 12/12/2026

One-way

Basic

From
$138
Seen: 13 hrs ago

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 12/01/2026

One-way

Basic

From
$138
Seen: 14 hrs ago

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 11/22/2026

One-way

Basic

From
$145
Seen: 13 hrs ago

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Basic

From
$145
Seen: 13 hrs ago

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 12/01/2026

One-way

Choice

From
$182
Seen: 14 hrs ago

Manchester, NH (MHT)to

Knoxville (TYS)
Depart: 12/12/2026

One-way

Choice

From
$182
Seen: 13 hrs ago

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Explore flights from Manchester, NH to Knoxville

Oct 2026
From$335*
Seen: 10 hrs ago
One Way/Basic
Nov 2026
From$145*
Seen: 13 hrs ago
One Way/Basic
Dec 2026
From$138*
Seen: 14 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $145
Displaying fares for October-2026
  • MHT–TYS, 10/23/2026: From $394
    23

    Fri

    OCT

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    24

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    27

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    28

    Wed

  • MHT–TYS, 10/29/2026: From $335
    29

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    30

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    31

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    01

    Sun

    NOV

  • MHT–TYS, 11/02/2026: From $335
    02

    Mon

  • MHT–TYS, 11/03/2026: From $269
    03

    Tue

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    04

    Wed

  • MHT–TYS, 11/05/2026: From $279
    05

    Thu

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    06

    Fri

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    07

    Sat

  • MHT–TYS, 11/08/2026: From $264
    08

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    09

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    10

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    11

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    12

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  • MHT–TYS, 11/13/2026: From $145
    13

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    14

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    15

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    16

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    17

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    18

    Wed

  • MHT–TYS, 11/19/2026: From $314
    19

    Thu

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    20

    Fri

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    21

    Sat

  • MHT–TYS, 11/22/2026: From $145
    22

    Sun

    • Range$145-$394

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Manchester-Boston Regional Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    831 miles

    Questions we hear the most

    There are 42 weekly flights from Manchester, NH to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Manchester, NH to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Manchester, NH to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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