Southwest® flights from Panama City Beach, FL to Chicago (O'Hare)

Promo Code

Low fares from Panama City Beach, FL to Chicago (O'Hare)

$

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 09/19/2026

One-way

Basic

From
$175
Seen: 19 hrs ago

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 08/31/2026

One-way

Basic

From
$175
Seen: 9 hrs ago

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 09/03/2026

One-way

Basic

From
$175
Seen: 5 hrs ago

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 09/10/2026

One-way

Basic

From
$175
Seen: 21 hrs ago

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 09/24/2026

One-way

Basic

From
$175
Seen: 7 hrs ago

Panama City Beach, FL (ECP)to

Chicago (Midway) (MDW)
Depart: 08/25/2026

One-way

Basic

From
$185
Seen: 14 hrs ago

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Explore flights from Panama City Beach, FL to Chicago (O'Hare)

Aug 2026
From$175*
Seen: 9 hrs ago
One Way/Basic
Sep 2026
From$175*
Seen: 21 hrs ago
One Way/Basic
Oct 2026
From$210*
Seen: 1 hour ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $175
cmp-daily-histogram-bars-legend-max-price-aria-label $263
Displaying fares for August-2026
  • ECP–MDW, 08/05/2026: From $220
    05

    Wed

    AUG

  • ECP–MDW, 08/06/2026: From $242
    06

    Thu

  • ECP–MDW, 08/07/2026: From $252
    07

    Fri

  • ECP–MDW, 08/08/2026: From $247
    08

    Sat

  • ECP–MDW, 08/09/2026: From $263
    09

    Sun

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    10

    Mon

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    11

    Tue

  • ECP–MDW, 08/12/2026: From $220
    12

    Wed

  • ECP–MDW, 08/13/2026: From $242
    13

    Thu

  • ECP–MDW, 08/14/2026: From $252
    14

    Fri

  • ECP–MDW, 08/15/2026: From $210
    15

    Sat

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    16

    Sun

  • ECP–MDW, 08/17/2026: From $252
    17

    Mon

  • ECP–MDW, 08/18/2026: From $220
    18

    Tue

  • ECP–MDW, 08/19/2026: From $220
    19

    Wed

  • ECP–MDW, 08/20/2026: From $242
    20

    Thu

  • ECP–MDW, 08/21/2026: From $242
    21

    Fri

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    22

    Sat

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    23

    Sun

  • ECP–MDW, 08/24/2026: From $242
    24

    Mon

  • ECP–MDW, 08/25/2026: From $185
    25

    Tue

  • ECP–MDW, 08/26/2026: From $185
    26

    Wed

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    27

    Thu

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    28

    Fri

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    29

    Sat

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    30

    Sun

  • ECP–MDW, 08/31/2026: From $175
    31

    Mon

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    SEP

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • ECP–MDW, 09/03/2026: From $175
    03

    Thu

  • ECP–MDW: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

    • Range$175-$263

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Northwest Florida Beaches International Airport
    Arriving at:
    O'Hare International Airport
    Distance:
    810 miles

    Route Information

    40† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 40 weekly flights from Panama City Beach, FL to Chicago (O'Hare) on Southwest Airlines.
    To find the lowest fares by day and time to fly Panama City Beach, FL to Chicago (O'Hare) with Southwest, check out our Low Fare Calendar.
    You can rent a car at O'Hare International Airport book yours with your flight.
    Yes! Flights from Panama City Beach, FL to Chicago (O'Hare)—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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