Southwest® flights from Pittsburgh to Knoxville from $153

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Low fares from Pittsburgh to Knoxville

$

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Basic

From
$153

Low fares from Pittsburgh to Knoxville

$

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Basic

From
$153
Seen: 23 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Choice

From
$188
Seen: 23 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/04/2026

One-way

Basic

From
$188
Seen: 23 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/02/2026

One-way

Basic

From
$188
Seen: 18 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/04/2026

One-way

Choice

From
$223
Seen: 23 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/02/2026

One-way

Choice

From
$223
Seen: 18 hrs ago
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Explore flights from Pittsburgh to Knoxville

cmp-daily-histogram-bars-legend-min-price-aria-label $153
cmp-daily-histogram-bars-legend-max-price-aria-label $506
Displaying fares for November-2026
  • PIT–TYS, 11/13/2026: From $351
    13

    Fri

    NOV

  • PIT–TYS, 11/14/2026: From $275
    14

    Sat

  • PIT–TYS, 11/15/2026: From $351
    15

    Sun

  • PIT–TYS, 11/16/2026: From $351
    16

    Mon

  • PIT–TYS, 11/17/2026: From $260
    17

    Tue

  • PIT–TYS, 11/18/2026: From $260
    18

    Wed

  • PIT–TYS, 11/19/2026: From $378
    19

    Thu

  • PIT–TYS, 11/20/2026: From $481
    20

    Fri

  • PIT–TYS, 11/21/2026: From $275
    21

    Sat

  • PIT–TYS, 11/22/2026: From $344
    22

    Sun

  • PIT–TYS, 11/23/2026: From $344
    23

    Mon

  • PIT–TYS, 11/24/2026: From $260
    24

    Tue

  • PIT–TYS, 11/25/2026: From $249
    25

    Wed

  • PIT–TYS, 11/26/2026: From $249
    26

    Thu

  • PIT–TYS, 11/27/2026: From $249
    27

    Fri

  • PIT–TYS, 11/28/2026: From $280
    28

    Sat

  • PIT–TYS, 11/29/2026: From $506
    29

    Sun

  • PIT–TYS, 11/30/2026: From $279
    30

    Mon

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • PIT–TYS, 12/02/2026: From $188
    02

    Wed

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • PIT–TYS, 12/04/2026: From $188
    04

    Fri

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • PIT–TYS, 12/07/2026: From $269
    07

    Mon

  • PIT–TYS, 12/08/2026: From $153
    08

    Tue

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • Range$153-$506

    Flight Details

    Departing from:
    Pittsburgh International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    382 miles

    Questions we hear the most

    There are 50 weekly flights from Pittsburgh to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Pittsburgh to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Pittsburgh to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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