Southwest® flights from Pittsburgh to Knoxville from $156

Promo Code

Low fares from Pittsburgh to Knoxville

$

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/09/2026

One-way

Basic

From
$156

Low fares from Pittsburgh to Knoxville

$

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 12/09/2026

One-way

Basic

From
$156
Seen: 16 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 11/04/2026

One-way

Basic

From
$156
Seen: 19 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 11/23/2026

One-way

Basic

From
$163
Seen: 15 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 10/30/2026

One-way

Basic

From
$166
Seen: 18 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 10/27/2026

One-way

Basic

From
$166
Seen: 14 hrs ago

Pittsburgh (PIT)to

Knoxville (TYS)
Depart: 10/28/2026

One-way

Basic

From
$166
Seen: 14 hrs ago

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Explore flights from Pittsburgh to Knoxville

Oct 2026
From$166*
Seen: 18 hrs ago
One Way/Basic
Nov 2026
From$156*
Seen: 19 hrs ago
One Way/Basic
Dec 2026
From$156*
Seen: 16 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $166
cmp-daily-histogram-bars-legend-max-price-aria-label $373
Displaying fares for October-2026
  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

    OCT

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • PIT–TYS, 10/05/2026: From $336
    05

    Mon

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • PIT–TYS, 10/07/2026: From $245
    07

    Wed

  • PIT–TYS, 10/08/2026: From $336
    08

    Thu

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    09

    Fri

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    13

    Tue

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    14

    Wed

  • PIT–TYS, 10/15/2026: From $373
    15

    Thu

  • PIT–TYS, 10/16/2026: From $363
    16

    Fri

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • PIT–TYS, 10/18/2026: From $244
    18

    Sun

  • PIT–TYS, 10/19/2026: From $234
    19

    Mon

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    20

    Tue

  • PIT–TYS, 10/21/2026: From $239
    21

    Wed

  • PIT–TYS, 10/22/2026: From $234
    22

    Thu

  • PIT–TYS, 10/23/2026: From $254
    23

    Fri

  • PIT–TYS, 10/24/2026: From $166
    24

    Sat

  • PIT–TYS, 10/25/2026: From $218
    25

    Sun

  • PIT–TYS, 10/26/2026: From $166
    26

    Mon

  • PIT–TYS, 10/27/2026: From $166
    27

    Tue

  • PIT–TYS, 10/28/2026: From $166
    28

    Wed

  • PIT–TYS, 10/29/2026: From $190
    29

    Thu

  • PIT–TYS, 10/30/2026: From $166
    30

    Fri

  • PIT–TYS: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • PIT–TYS, 11/01/2026: From $218
    01

    Sun

    NOV

  • PIT–TYS, 11/02/2026: From $174
    02

    Mon

    • Range$166-$373

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Pittsburgh International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    382 miles

    Route Information

    50† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 50 weekly flights from Pittsburgh to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Pittsburgh to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Pittsburgh to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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