Southwest® flights from Tampa to Knoxville from $158

Promo Code

Low fares from Tampa to Knoxville

$

Tampa (TPA)to

Knoxville (TYS)
Depart: 11/07/2026

One-way

Basic

From
$158

Low fares from Tampa to Knoxville

$

Tampa (TPA)to

Knoxville (TYS)
Depart: 11/07/2026

One-way

Basic

From
$158
Seen: 21 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 09/29/2026

One-way

Basic

From
$158
Seen: 12 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Basic

From
$158
Seen: 7 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 11/05/2026

One-way

Basic

From
$158
Seen: 23 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 10/14/2026

One-way

Basic

From
$158
Seen: 8 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 09/22/2026

One-way

Basic

From
$158
Seen: 9 hrs ago

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Explore flights from Tampa to Knoxville

Try alternate month or interact with individual days below in order to find offers.
Aug 2026
No result for this month.
Sep 2026
From$158*
Seen: 12 hrs ago
One Way/Basic
Oct 2026
From$158*
Seen: 8 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $158
cmp-daily-histogram-bars-legend-max-price-aria-label $343
Displaying fares for August-2026
  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    31

    Mon

    AUG

  • TPA–TYS, 09/01/2026: From $343
    01

    Tue

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    02

    Wed

  • TPA–TYS, 09/03/2026: From $343
    03

    Thu

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    04

    Fri

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    05

    Sat

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    06

    Sun

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • TPA–TYS, 09/08/2026: From $324
    08

    Tue

  • TPA–TYS, 09/09/2026: From $324
    09

    Wed

  • TPA–TYS, 09/10/2026: From $324
    10

    Thu

  • TPA–TYS, 09/11/2026: From $324
    11

    Fri

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • TPA–TYS, 09/13/2026: From $230
    13

    Sun

  • TPA–TYS, 09/14/2026: From $230
    14

    Mon

  • TPA–TYS, 09/15/2026: From $230
    15

    Tue

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • TPA–TYS, 09/17/2026: From $235
    17

    Thu

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • TPA–TYS, 09/20/2026: From $208
    20

    Sun

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    21

    Mon

  • TPA–TYS, 09/22/2026: From $158
    22

    Tue

  • TPA–TYS, 09/23/2026: From $158
    23

    Wed

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

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    25

    Fri

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    26

    Sat

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    27

    Sun

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • TPA–TYS, 09/29/2026: From $158
    29

    Tue

  • TPA–TYS: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

    • Range$158-$343

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Tampa International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    547 miles

    Route Information

    55† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 55 weekly flights from Tampa to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Tampa to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Tampa to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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