Southwest® flights from Buffalo/Niagara Falls to Greenville-Spartanburg from $135

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Low fares from Buffalo/Niagara Falls to Greenville-Spartanburg

$

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 01/11/2027

One-way

Basic

From
$135
Seen: 9 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/10/2026

One-way

Basic

From
$135
Seen: 10 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/09/2026

One-way

Basic

From
$135
Seen: 16 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/19/2026

One-way

Basic

From
$140
Seen: 20 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 01/10/2027

One-way

Basic

From
$145
Seen: 10 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 01/13/2027

One-way

Basic

From
$163
Seen: 21 hrs ago

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Explore flights from Buffalo/Niagara Falls to Greenville-Spartanburg

Oct 2026
From$429*
Seen: 3 hrs ago
One Way/Basic
Nov 2026
From$135*
Seen: 16 hrs ago
One Way/Basic
Dec 2026
From$197*
Seen: 4 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $135
Displaying fares for October-2026
  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
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  • BUF–GSP, 10/27/2026: From $429
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    NOV

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  • BUF–GSP, 11/08/2026: From $259
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  • BUF–GSP, 11/09/2026: From $135
    09

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  • BUF–GSP, 11/10/2026: From $135
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  • BUF–GSP, 11/13/2026: From $259
    13

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    18

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  • BUF–GSP, 11/19/2026: From $140
    19

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    • Range$135-$429

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Greenville-Spartanburg International Airport
    Distance:
    586 miles

    Questions we hear the most

    There are 52 weekly flights from Buffalo/Niagara Falls to Greenville-Spartanburg on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
    You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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