Southwest® flights from Buffalo/Niagara Falls to Greenville-Spartanburg from $199

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Low fares from Buffalo/Niagara Falls to Greenville-Spartanburg

$

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 10/30/2026

One-way

Basic

From
$199
Seen: 14 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 12/22/2026

One-way

Basic

From
$199
Seen: 13 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 10/17/2026

One-way

Basic

From
$199
Seen: 3 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/17/2026

One-way

Basic

From
$199
Seen: 18 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 10/14/2026

One-way

Basic

From
$199
Seen: 9 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 10/03/2026

One-way

Basic

From
$199
Seen: 1 hour ago

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Explore flights from Buffalo/Niagara Falls to Greenville-Spartanburg

Sep 2026
From$249*
Seen: 4 hrs ago
One Way/Basic
Oct 2026
From$199*
Seen: 9 hrs ago
One Way/Basic
Nov 2026
From$199*
Seen: 15 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $199
cmp-daily-histogram-bars-legend-max-price-aria-label $559
Displaying fares for September-2026
  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

    SEP

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • BUF–GSP, 09/15/2026: From $419
    15

    Tue

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • BUF–GSP, 09/17/2026: From $419
    17

    Thu

  • BUF–GSP, 09/18/2026: From $559
    18

    Fri

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

  • BUF–GSP, 09/25/2026: From $344
    25

    Fri

  • BUF–GSP, 09/26/2026: From $249
    26

    Sat

  • BUF–GSP, 09/27/2026: From $249
    27

    Sun

  • BUF–GSP, 09/28/2026: From $496
    28

    Mon

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • BUF–GSP, 10/01/2026: From $419
    01

    Thu

    OCT

  • BUF–GSP, 10/02/2026: From $264
    02

    Fri

  • BUF–GSP, 10/03/2026: From $199
    03

    Sat

  • BUF–GSP, 10/04/2026: From $209
    04

    Sun

  • BUF–GSP, 10/05/2026: From $313
    05

    Mon

  • BUF–GSP, 10/06/2026: From $199
    06

    Tue

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    07

    Wed

  • BUF–GSP, 10/08/2026: From $313
    08

    Thu

  • BUF–GSP, 10/09/2026: From $419
    09

    Fri

  • BUF–GSP, 10/10/2026: From $259
    10

    Sat

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

    • Range$199-$559

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Greenville-Spartanburg International Airport
    Distance:
    586 miles

    Route Information

    52† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 52 weekly flights from Buffalo/Niagara Falls to Greenville-Spartanburg on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
    You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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