Southwest® flights from Buffalo/Niagara Falls to Greenville-Spartanburg from $155

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Low fares from Buffalo/Niagara Falls to Greenville-Spartanburg

$

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 09/10/2026

One-way

Basic

From
$155
Seen: 8 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/18/2026

One-way

Basic

From
$155
Seen: 14 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/05/2026

One-way

Basic

From
$184
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/18/2026

One-way

Choice

From
$195
Seen: 14 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 11/21/2026

One-way

Basic

From
$195
Seen: 3 hrs ago

Buffalo/Niagara Falls (BUF)to

Greenville-Spartanburg (GSP)
Depart: 09/10/2026

One-way

Choice

From
$195
Seen: 8 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

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Explore flights from Buffalo/Niagara Falls to Greenville-Spartanburg

Aug 2026
From$409*
Seen: 9 hrs ago
One Way/Basic
Sep 2026
From$155*
Seen: 8 hrs ago
One Way/Basic
Oct 2026
From$303*
Seen: 23 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $155
Displaying fares for August-2026
  • BUF–GSP: cmp-view-offers-disclaimer. Find Offers
    24

    Mon

    AUG

  • BUF–GSP, 08/25/2026: From $409
    25

    Tue

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    26

    Wed

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    27

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    28

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    29

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    30

    Sun

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    31

    Mon

  • BUF–GSP, 09/01/2026: From $334
    01

    Tue

    SEP

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    02

    Wed

  • BUF–GSP, 09/03/2026: From $334
    03

    Thu

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    04

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    05

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    06

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    07

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    08

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    09

    Wed

  • BUF–GSP, 09/10/2026: From $155
    10

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    11

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    12

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    13

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    14

    Mon

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    15

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    16

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    17

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    18

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    19

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    20

    Sun

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    21

    Mon

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    22

    Tue

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    23

    Wed

    • Range$155-$409

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Greenville-Spartanburg International Airport
    Distance:
    586 miles

    Route Information

    52† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 52 weekly flights from Buffalo/Niagara Falls to Greenville-Spartanburg on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
    You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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