Southwest® flights from Chicago-Midway to Knoxville from $106

Promo Code

Low fares from Chicago-Midway to Knoxville

$

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 11/10/2026

One-way

Basic

From
$106

Low fares from Chicago-Midway to Knoxville

$

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 11/10/2026

One-way

Basic

From
$106
Seen: 20 hrs ago

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 12/05/2026

One-way

Basic

From
$106
Seen: 20 hrs ago

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 12/04/2026

One-way

Basic

From
$133
Seen: 14 hrs ago

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 01/08/2027

One-way

Basic

From
$133
Seen: 13 minutes ago

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 11/11/2026

One-way

Basic

From
$133
Seen: 9 hrs ago

Chicago-Midway (MDW)to

Knoxville (TYS)
Depart: 01/09/2027

One-way

Basic

From
$133
Seen: 17 minutes ago

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Explore flights from Chicago-Midway to Knoxville

Oct 2026
From$175*
Seen: 46 minutes ago
One Way/Basic
Nov 2026
From$106*
Seen: 20 hrs ago
One Way/Basic
Dec 2026
From$106*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $137
cmp-daily-histogram-bars-legend-max-price-aria-label $300
Displaying fares for October-2026
  • MDW–TYS, 10/10/2026: From $225
    10

    Sat

    OCT

  • MDW–TYS, 10/11/2026: From $300
    11

    Sun

  • MDW–TYS, 10/12/2026: From $260
    12

    Mon

  • MDW–TYS, 10/13/2026: From $225
    13

    Tue

  • MDW–TYS, 10/14/2026: From $225
    14

    Wed

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    15

    Thu

  • MDW–TYS, 10/16/2026: From $288
    16

    Fri

  • MDW–TYS, 10/17/2026: From $205
    17

    Sat

  • MDW–TYS, 10/18/2026: From $260
    18

    Sun

  • MDW–TYS, 10/19/2026: From $205
    19

    Mon

  • MDW–TYS, 10/20/2026: From $205
    20

    Tue

  • MDW–TYS, 10/21/2026: From $205
    21

    Wed

  • MDW–TYS, 10/22/2026: From $230
    22

    Thu

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • MDW–TYS, 10/24/2026: From $180
    24

    Sat

  • MDW–TYS, 10/25/2026: From $250
    25

    Sun

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • MDW–TYS, 10/29/2026: From $175
    29

    Thu

  • MDW–TYS, 10/30/2026: From $175
    30

    Fri

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    01

    Sun

    NOV

  • MDW–TYS, 11/02/2026: From $175
    02

    Mon

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • MDW–TYS, 11/04/2026: From $137
    04

    Wed

  • MDW–TYS, 11/05/2026: From $229
    05

    Thu

  • MDW–TYS, 11/06/2026: From $300
    06

    Fri

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • MDW–TYS: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

    • Range$137-$300

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Chicago Midway International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    459 miles

    Questions we hear the most

    There are 71 weekly flights from Chicago (Midway) to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Chicago (Midway) to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Chicago (Midway) to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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