Southwest® flights from Denver to Knoxville from $177

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Low fares from Denver to Knoxville

$

Denver (DEN)to

Knoxville (TYS)
Depart: 01/16/2027

One-way

Basic

From
$177

Low fares from Denver to Knoxville

$

Denver (DEN)to

Knoxville (TYS)
Depart: 01/16/2027

One-way

Basic

From
$177
Seen: 15 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 12/09/2026

One-way

Basic

From
$177
Seen: 12 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 02/17/2027

One-way

Basic

From
$177
Seen: 12 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Basic

From
$177
Seen: 19 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 12/12/2026

One-way

Basic

From
$177
Seen: 8 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 12/15/2026

One-way

Basic

From
$187
Seen: 10 hrs ago

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Explore flights from Denver to Knoxville

Nov 2026
From$394*
Seen: 21 hrs ago
One Way/Basic
Dec 2026
From$177*
Seen: 19 hrs ago
One Way/Basic
Jan 2027
From$177*
Seen: 15 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $177
cmp-daily-histogram-bars-legend-max-price-aria-label $584
Displaying fares for November-2026
  • DEN–TYS, 11/14/2026: From $424
    14

    Sat

    NOV

  • DEN–TYS, 11/15/2026: From $424
    15

    Sun

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • DEN–TYS, 11/17/2026: From $419
    17

    Tue

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • DEN–TYS, 11/19/2026: From $434
    19

    Thu

  • DEN–TYS, 11/20/2026: From $584
    20

    Fri

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • DEN–TYS, 11/22/2026: From $394
    22

    Sun

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • DEN–TYS, 11/25/2026: From $409
    25

    Wed

  • DEN–TYS, 11/26/2026: From $399
    26

    Thu

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    29

    Sun

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • DEN–TYS, 12/01/2026: From $304
    01

    Tue

    DEC

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • DEN–TYS, 12/03/2026: From $212
    03

    Thu

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

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    05

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • DEN–TYS, 12/07/2026: From $197
    07

    Mon

  • DEN–TYS, 12/08/2026: From $177
    08

    Tue

  • DEN–TYS, 12/09/2026: From $177
    09

    Wed

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • DEN–TYS, 12/12/2026: From $177
    12

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

    • Range$177-$584

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Average flight time:
    2 hours 47 minutes
    Distance:
    1162 miles

    Questions we hear the most

    The average flight time from Denver to Knoxville is 2 hours 47 minutes.
    There are 67 weekly flights from Denver to Knoxville on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to Knoxville once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Denver to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Denver to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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