Southwest® flights from Denver to Knoxville from $199

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Low fares from Denver to Knoxville

$

Denver (DEN)to

Knoxville (TYS)
Depart: 10/27/2026

One-way

Basic

From
$199

Low fares from Denver to Knoxville

$

Denver (DEN)to

Knoxville (TYS)
Depart: 10/27/2026

One-way

Basic

From
$199
Seen: 23 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 11/03/2026

One-way

Basic

From
$199
Seen: 21 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 11/17/2026

One-way

Basic

From
$199
Seen: 17 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 11/11/2026

One-way

Basic

From
$199
Seen: 1 hour ago

Denver (DEN)to

Knoxville (TYS)
Depart: 11/18/2026

One-way

Basic

From
$199
Seen: 20 hrs ago

Denver (DEN)to

Knoxville (TYS)
Depart: 11/04/2026

One-way

Basic

From
$209
Seen: 19 hrs ago

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Explore flights from Denver to Knoxville

Sep 2026
From$284*
Seen: 20 hrs ago
One Way/Basic
Oct 2026
From$199*
Seen: 23 hrs ago
One Way/Basic
Nov 2026
From$199*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $219
cmp-daily-histogram-bars-legend-max-price-aria-label $469
Displaying fares for September-2026
  • DEN–TYS, 09/14/2026: From $404
    14

    Mon

    SEP

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • DEN–TYS, 09/16/2026: From $414
    16

    Wed

  • DEN–TYS, 09/17/2026: From $414
    17

    Thu

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • DEN–TYS, 09/19/2026: From $379
    19

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • DEN–TYS, 09/22/2026: From $389
    22

    Tue

  • DEN–TYS, 09/23/2026: From $379
    23

    Wed

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

  • DEN–TYS, 09/26/2026: From $294
    26

    Sat

  • DEN–TYS, 09/27/2026: From $284
    27

    Sun

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • DEN–TYS, 09/30/2026: From $294
    30

    Wed

  • DEN–TYS, 10/01/2026: From $299
    01

    Thu

    OCT

  • DEN–TYS, 10/02/2026: From $334
    02

    Fri

  • DEN–TYS, 10/03/2026: From $235
    03

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • DEN–TYS, 10/05/2026: From $235
    05

    Mon

  • DEN–TYS, 10/06/2026: From $245
    06

    Tue

  • DEN–TYS, 10/07/2026: From $245
    07

    Wed

  • DEN–TYS, 10/08/2026: From $469
    08

    Thu

  • DEN–TYS, 10/09/2026: From $404
    09

    Fri

  • DEN–TYS, 10/10/2026: From $464
    10

    Sat

  • DEN–TYS: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • DEN–TYS, 10/12/2026: From $314
    12

    Mon

  • DEN–TYS, 10/13/2026: From $219
    13

    Tue

    • Range$219-$469

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Average flight time:
    2 hours 47 minutes
    Distance:
    1162 miles

    Route Information

    67† Weekly flights
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Denver to Knoxville is 2 hours 47 minutes.
    There are 67 weekly flights from Denver to Knoxville on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to Knoxville once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Denver to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Denver to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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