Southwest® flights from Detroit to San Diego from $220

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Low fares from Detroit to San Diego

$

Detroit (DTW)to

San Diego (SAN)
Depart: 12/22/2026

One-way

Basic

From
$220
Seen: 22 hrs ago

Detroit (DTW)to

San Diego (SAN)
Depart: 01/23/2027

One-way

Basic

From
$220
Seen: 14 hrs ago

Detroit (DTW)to

San Diego (SAN)
Depart: 02/17/2027

One-way

Basic

From
$229
Seen: 10 hrs ago

Detroit (DTW)to

San Diego (SAN)
Depart: 02/20/2027

One-way

Basic

From
$229
Seen: 9 hrs ago

Detroit (DTW)to

San Diego (SAN)
Depart: 12/23/2026

One-way

Basic

From
$229
Seen: 10 hrs ago

Detroit (DTW)to

San Diego (SAN)
Depart: 01/16/2027

One-way

Basic

From
$229
Seen: 8 hrs ago

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Explore flights from Detroit to San Diego

Nov 2026
From$365*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$220*
Seen: 22 hrs ago
One Way/Basic
Jan 2027
From$220*
Seen: 14 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $229
cmp-daily-histogram-bars-legend-max-price-aria-label $540
Displaying fares for November-2026
  • DTW–SAN, 11/12/2026: From $540
    12

    Thu

    NOV

  • DTW–SAN, 11/13/2026: From $535
    13

    Fri

  • DTW–SAN, 11/14/2026: From $535
    14

    Sat

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • DTW–SAN, 11/16/2026: From $535
    16

    Mon

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • DTW–SAN, 11/22/2026: From $415
    22

    Sun

  • DTW–SAN, 11/23/2026: From $415
    23

    Mon

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    25

    Wed

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • DTW–SAN, 11/28/2026: From $365
    28

    Sat

  • DTW–SAN, 11/29/2026: From $500
    29

    Sun

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • DTW–SAN, 12/01/2026: From $365
    01

    Tue

    DEC

  • DTW–SAN, 12/02/2026: From $229
    02

    Wed

  • DTW–SAN, 12/03/2026: From $249
    03

    Thu

  • DTW–SAN, 12/04/2026: From $264
    04

    Fri

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    05

    Sat

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • DTW–SAN: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

    • Range$229-$540

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Wayne County Airport
    Arriving at:
    San Diego International Airport
    Distance:
    1956 miles

    Questions we hear the most

    There are 123 weekly flights from Detroit to San Diego on Southwest Airlines.
    To find the lowest fares by day and time to fly Detroit to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Detroit to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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