Southwest® flights from Detroit to Myrtle Beach from $165

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Low fares from Detroit to Myrtle Beach

$

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 12/05/2026

One-way

Basic

From
$165
Seen: 23 hrs ago

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 12/02/2026

One-way

Basic

From
$165
Seen: 21 hrs ago

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 01/11/2027

One-way

Basic

From
$185
Seen: 18 hrs ago

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 01/21/2027

One-way

Basic

From
$185
Seen: 17 hrs ago

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 12/05/2026

One-way

Choice

From
$205
Seen: 23 hrs ago

Detroit (DTW)to

Myrtle Beach (MYR)
Depart: 12/02/2026

One-way

Choice

From
$205
Seen: 21 hrs ago

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Explore flights from Detroit to Myrtle Beach

Nov 2026
From$295*
Seen: 19 hrs ago
One Way/Basic
Dec 2026
From$165*
Seen: 23 hrs ago
One Way/Basic
Jan 2027
From$185*
Seen: 17 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $165
cmp-daily-histogram-bars-legend-max-price-aria-label $375
Displaying fares for November-2026
  • DTW–MYR, 11/13/2026: From $375
    13

    Fri

    NOV

  • DTW–MYR, 11/14/2026: From $375
    14

    Sat

  • DTW–MYR, 11/15/2026: From $375
    15

    Sun

  • DTW–MYR, 11/16/2026: From $375
    16

    Mon

  • DTW–MYR, 11/17/2026: From $375
    17

    Tue

  • DTW–MYR, 11/18/2026: From $325
    18

    Wed

  • DTW–MYR, 11/19/2026: From $325
    19

    Thu

  • DTW–MYR, 11/20/2026: From $325
    20

    Fri

  • DTW–MYR, 11/21/2026: From $325
    21

    Sat

  • DTW–MYR, 11/22/2026: From $325
    22

    Sun

  • DTW–MYR, 11/23/2026: From $325
    23

    Mon

  • DTW–MYR, 11/24/2026: From $350
    24

    Tue

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    25

    Wed

  • DTW–MYR, 11/26/2026: From $295
    26

    Thu

  • DTW–MYR, 11/27/2026: From $295
    27

    Fri

  • DTW–MYR, 11/28/2026: From $325
    28

    Sat

  • DTW–MYR, 11/29/2026: From $325
    29

    Sun

  • DTW–MYR, 11/30/2026: From $325
    30

    Mon

  • DTW–MYR, 12/01/2026: From $295
    01

    Tue

    DEC

  • DTW–MYR, 12/02/2026: From $165
    02

    Wed

  • DTW–MYR, 12/03/2026: From $210
    03

    Thu

  • DTW–MYR, 12/04/2026: From $225
    04

    Fri

  • DTW–MYR, 12/05/2026: From $165
    05

    Sat

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • DTW–MYR: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

    • Range$165-$375

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Wayne County Airport
    Arriving at:
    Myrtle Beach International Airport
    Distance:
    636 miles

    Questions we hear the most

    There are 65 weekly flights from Detroit to Myrtle Beach on Southwest Airlines.
    To find the lowest fares by day and time to fly Detroit to Myrtle Beach with Southwest, check out our Low Fare Calendar.
    You can rent a car at Myrtle Beach International Airport book yours with your flight.
    Yes! Flights from Detroit to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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