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Find low faresSouthwest® flights from Greenville-Spartanburg to Indianapolis from $128
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1 Passenger
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Low fares from Greenville-Spartanburg to Indianapolis
$
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/03/2026
One-way
Basic
From
$128
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/04/2026
One-way
Basic
From
$128
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/03/2026
One-way
Choice
From
$158
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/04/2026
One-way
Choice
From
$158
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/02/2026
One-way
Basic
From
$164
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Indianapolis (IND)
Depart: 03/05/2026
One-way
Basic
From
$174
Seen: 21 hrs ago
Explore flights from Greenville-Spartanburg to Indianapolis
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Flight Details
Departing from:
Greenville-Spartanburg International Airport
Arriving at:
Indianapolis International Airport
Distance:
401 miles
Route Information
59† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 59 weekly flights from Greenville-Spartanburg to Indianapolis on Southwest Airlines.
To find the lowest fares by day and time to fly Greenville-Spartanburg to Indianapolis with Southwest, check out our Low Fare Calendar.
You can rent a car at Indianapolis International Airport book yours with your flight.
Yes! Flights from Greenville-Spartanburg to Indianapolis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.