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Find low faresSouthwest® flights from Greenville-Spartanburg to Milwaukee from $163
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1 Passenger
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Low fares from Greenville-Spartanburg to Milwaukee
$
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 04/20/2026
One-way
Basic
From
$163
Seen: 17 hrs ago
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 04/20/2026
One-way
Choice
From
$198
Seen: 17 hrs ago
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 02/18/2026
One-way
Basic
From
$229
Seen: 16 hrs ago
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 02/18/2026
One-way
Choice
From
$264
Seen: 16 hrs ago
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 04/20/2026
One-way
Choice Preferred
From
$268
Seen: 17 hrs ago
Greenville-Spartanburg (GSP)to
Milwaukee (MKE)
Depart: 04/20/2026
One-way
Choice Extra
From
$318
Seen: 17 hrs ago
Explore flights from Greenville-Spartanburg to Milwaukee
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Flight Details
Departing from:
Greenville-Spartanburg International Airport
Arriving at:
General Mitchell Airport
Distance:
634 miles
Route Information
51† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 51 weekly flights from Greenville-Spartanburg to Milwaukee on Southwest Airlines.
To find the lowest fares by day and time to fly Greenville-Spartanburg to Milwaukee with Southwest, check out our Low Fare Calendar.
You can rent a car at General Mitchell Airport book yours with your flight.
Yes! Flights from Greenville-Spartanburg to Milwaukee—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.