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Find low faresSouthwest® flights from Greenville-Spartanburg to Fort Myers/Naples from $160
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1 Passenger
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Low fares from Greenville-Spartanburg to Fort Myers/Naples
$
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 03/10/2026
One-way
Basic
From
$160
Seen: 8 hrs ago
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 04/04/2026
One-way
Basic
From
$163
Seen: 20 hrs ago
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 03/14/2026
One-way
Basic
From
$184
Seen: 4 hrs ago
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 03/21/2026
One-way
Basic
From
$184
Seen: 21 hrs ago
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 04/17/2026
One-way
Basic
From
$189
Seen: 4 hrs ago
Greenville-Spartanburg (GSP)to
Fort Myers/Naples (RSW)
Depart: 03/12/2026
One-way
Basic
From
$189
Seen: 19 hrs ago
Explore flights from Greenville-Spartanburg to Fort Myers/Naples
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Flight Details
Departing from:
Greenville-Spartanburg International Airport
Arriving at:
Southwest Florida Regional Airport
Distance:
577 miles
Route Information
54† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 54 weekly flights from Greenville-Spartanburg to Fort Myers/Naples on Southwest Airlines.
To find the lowest fares by day and time to fly Greenville-Spartanburg to Fort Myers/Naples with Southwest, check out our Low Fare Calendar.
You can rent a car at Southwest Florida Regional Airport book yours with your flight.
Yes! Flights from Greenville-Spartanburg to Fort Myers/Naples—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.