Southwest® flights from Greenville-Spartanburg to St. Louis from $167

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Low fares from Greenville-Spartanburg to St. Louis

$

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 12/08/2026

One-way

Basic

From
$167
Seen: 16 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$167
Seen: 9 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 01/12/2027

One-way

Basic

From
$167
Seen: 10 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 12/09/2026

One-way

Basic

From
$167
Seen: 22 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 12/05/2026

One-way

Basic

From
$167
Seen: 13 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$167
Seen: 13 hrs ago

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Explore flights from Greenville-Spartanburg to St. Louis

Nov 2026
From$254*
Seen: 7 hrs ago
One Way/Basic
Dec 2026
From$167*
Seen: 9 hrs ago
One Way/Basic
Jan 2027
From$167*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $167
cmp-daily-histogram-bars-legend-max-price-aria-label $366
Displaying fares for November-2026
  • GSP–STL, 11/11/2026: From $320
    11

    Wed

    NOV

  • GSP–STL, 11/12/2026: From $366
    12

    Thu

  • GSP–STL, 11/13/2026: From $366
    13

    Fri

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • GSP–STL, 11/16/2026: From $359
    16

    Mon

  • GSP–STL, 11/17/2026: From $320
    17

    Tue

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • GSP–STL, 11/19/2026: From $359
    19

    Thu

  • GSP–STL, 11/20/2026: From $359
    20

    Fri

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • GSP–STL, 11/24/2026: From $264
    24

    Tue

  • GSP–STL, 11/25/2026: From $264
    25

    Wed

  • GSP–STL, 11/26/2026: From $269
    26

    Thu

  • GSP–STL, 11/27/2026: From $264
    27

    Fri

  • GSP–STL, 11/28/2026: From $299
    28

    Sat

  • GSP–STL, 11/29/2026: From $294
    29

    Sun

  • GSP–STL, 11/30/2026: From $254
    30

    Mon

  • GSP–STL, 12/01/2026: From $192
    01

    Tue

    DEC

  • GSP–STL, 12/02/2026: From $167
    02

    Wed

  • GSP–STL, 12/03/2026: From $182
    03

    Thu

  • GSP–STL, 12/04/2026: From $192
    04

    Fri

  • GSP–STL, 12/05/2026: From $167
    05

    Sat

  • GSP–STL, 12/06/2026: From $224
    06

    Sun

  • GSP–STL, 12/07/2026: From $182
    07

    Mon

  • GSP–STL, 12/08/2026: From $167
    08

    Tue

  • GSP–STL, 12/09/2026: From $167
    09

    Wed

  • GSP–STL, 12/10/2026: From $187
    10

    Thu

    • Range$167-$366

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Greenville-Spartanburg International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    524 miles

    Questions we hear the most

    There are 53 weekly flights from Greenville-Spartanburg to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Greenville-Spartanburg to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Greenville-Spartanburg to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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