Southwest® flights from Greenville-Spartanburg to St. Louis from $130

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Low fares from Greenville-Spartanburg to St. Louis

$

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 10/17/2026

One-way

Basic

From
$130
Seen: 15 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 10/19/2026

One-way

Basic

From
$130
Seen: 14 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 11/18/2026

One-way

Basic

From
$130
Seen: 7 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 10/23/2026

One-way

Basic

From
$150
Seen: 12 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 10/16/2026

One-way

Basic

From
$150
Seen: 13 hrs ago

Greenville-Spartanburg (GSP)to

St. Louis (STL)
Depart: 10/30/2026

One-way

Basic

From
$150
Seen: 18 hrs ago

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Explore flights from Greenville-Spartanburg to St. Louis

Aug 2026
From$295*
Seen: 12 hrs ago
One Way/Basic
Sep 2026
From$239*
Seen: 14 hrs ago
One Way/Basic
Oct 2026
From$130*
Seen: 14 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $239
cmp-daily-histogram-bars-legend-max-price-aria-label $435
Displaying fares for August-2026
  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Fri

    AUG

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Sun

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    24

    Mon

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Tue

  • GSP–STL, 08/26/2026: From $295
    26

    Wed

  • GSP–STL, 08/27/2026: From $334
    27

    Thu

  • GSP–STL, 08/28/2026: From $334
    28

    Fri

  • GSP–STL, 08/29/2026: From $300
    29

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Sun

  • GSP–STL, 08/31/2026: From $334
    31

    Mon

  • GSP–STL, 09/01/2026: From $295
    01

    Tue

    SEP

  • GSP–STL, 09/02/2026: From $295
    02

    Wed

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • GSP–STL, 09/04/2026: From $239
    04

    Fri

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • GSP–STL, 09/08/2026: From $239
    08

    Tue

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • GSP–STL, 09/12/2026: From $435
    12

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Thu

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • GSP–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

    • Range$239-$435

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Greenville-Spartanburg International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    524 miles

    Route Information

    53† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 53 weekly flights from Greenville-Spartanburg to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Greenville-Spartanburg to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Greenville-Spartanburg to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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