Southwest® flights from Indianapolis to Knoxville from $208

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Low fares from Indianapolis to Knoxville

$

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/03/2026

One-way

Basic

From
$208

Low fares from Indianapolis to Knoxville

$

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/03/2026

One-way

Basic

From
$208
Seen: 18 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/11/2026

One-way

Basic

From
$209
Seen: 9 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/30/2026

One-way

Basic

From
$237
Seen: 9 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/03/2026

One-way

Choice

From
$243
Seen: 18 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 12/11/2026

One-way

Choice

From
$244
Seen: 9 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 01/02/2027

One-way

Basic

From
$258
Seen: 16 hrs ago

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Explore flights from Indianapolis to Knoxville

Nov 2026
From$344*
Seen: 8 hrs ago
One Way/Basic
Dec 2026
From$208*
Seen: 18 hrs ago
One Way/Basic
Jan 2027
From$258*
Seen: 16 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $208
cmp-daily-histogram-bars-legend-max-price-aria-label $369
Displaying fares for November-2026
  • IND–TYS, 11/12/2026: From $369
    12

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    NOV

  • IND–TYS, 11/13/2026: From $369
    13

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  • IND–TYS, 11/14/2026: From $369
    14

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    Tue

  • IND–TYS, 11/18/2026: From $344
    18

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  • IND–TYS, 11/21/2026: From $344
    21

    Sat

  • IND–TYS, 11/22/2026: From $344
    22

    Sun

  • IND–TYS, 11/23/2026: From $344
    23

    Mon

  • IND–TYS, 11/24/2026: From $344
    24

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    DEC

  • IND–TYS: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • IND–TYS, 12/03/2026: From $208
    03

    Thu

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    04

    Fri

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    09

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    10

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  • IND–TYS, 12/11/2026: From $209
    11

    Fri

    • Range$208-$369

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Indianapolis International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Distance:
    297 miles

    Questions we hear the most

    There are 56 weekly flights from Indianapolis to Knoxville on Southwest Airlines.
    To find the lowest fares by day and time to fly Indianapolis to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Indianapolis to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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