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Find low faresSouthwest® flights from St. Louis to Charlotte from $80
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Low fares from St. Louis to Charlotte
$
St. Louis (STL)to
Charlotte (CLT)
Depart: 02/21/2026
One-way
Basic
From
$80
Seen: 7 hrs ago
St. Louis (STL)to
Charlotte (CLT)
Depart: 02/28/2026
One-way
Basic
From
$80
Seen: 8 hrs ago
St. Louis (STL)to
Charlotte (CLT)
Depart: 02/25/2026
One-way
Basic
From
$96
Seen: 5 hrs ago
St. Louis (STL)to
Charlotte (CLT)
Depart: 03/21/2026
One-way
Basic
From
$106
Seen: 5 hrs ago
St. Louis (STL)to
Charlotte (CLT)
Depart: 04/04/2026
One-way
Basic
From
$107
Seen: 14 hrs ago
St. Louis (STL)to
Charlotte (CLT)
Depart: 04/25/2026
One-way
Basic
From
$107
Seen: 9 hrs ago
Explore flights from St. Louis to Charlotte
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Flight Details
Departing from:
Lambert-St Louis Int'l Airport
Arriving at:
Douglas Airport
Average flight time:
1 hour 50 minutes
Distance:
575 miles
Route Information
114† Weekly flights
- 1‡ Nonstop flight per day Monday through Friday
- 1‡ Nonstop flight on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from St. Louis to Charlotte is 1 hour 50 minutes.
There are 114 weekly flights from St. Louis to Charlotte on Southwest Airlines.
Yes, Southwest flies nonstop from St. Louis to Charlotte once per day from Monday through Friday.
Yes, Southwest flies nonstop from St. Louis to Charlotte once per day on Sundays.
To find the lowest fares by day and time to fly St. Louis to Charlotte with Southwest, check out our Low Fare Calendar.
You can rent a car at Douglas Airport book yours with your flight.
Yes! Flights from St. Louis to Charlotte—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.