Southwest® flights from St. Louis to San Diego from $176

Promo Code

Low fares from St. Louis to San Diego

$

St. Louis (STL)to

San Diego (SAN)
Depart: 10/24/2026

One-way

Basic

From
$176
Seen: 19 hrs ago

St. Louis (STL)to

San Diego (SAN)
Depart: 11/18/2026

One-way

Basic

From
$176
Seen: 15 minutes ago

St. Louis (STL)to

San Diego (SAN)
Depart: 12/09/2026

One-way

Basic

From
$176
Seen: 17 hrs ago

St. Louis (STL)to

San Diego (SAN)
Depart: 01/06/2027

One-way

Basic

From
$176
Seen: 2 hrs ago

St. Louis (STL)to

San Diego (SAN)
Depart: 10/29/2026

One-way

Basic

From
$176
Seen: 2 hrs ago

St. Louis (STL)to

San Diego (SAN)
Depart: 12/16/2026

One-way

Basic

From
$176
Seen: 1 hour ago

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Explore flights from St. Louis to San Diego

Sep 2026
From$630*
Seen: 19 hrs ago
One Way/Basic
Oct 2026
From$176*
Seen: 2 hrs ago
One Way/Basic
Nov 2026
From$176*
Seen: 1 hour ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $176
cmp-daily-histogram-bars-legend-max-price-aria-label $630
Displaying fares for September-2026
  • STL–SAN, 09/30/2026: From $630
    30

    Wed

    SEP

  • STL–SAN, 10/01/2026: From $630
    01

    Thu

  • STL–SAN, 10/02/2026: From $630
    02

    Fri

  • STL–SAN, 10/03/2026: From $625
    03

    Sat

  • STL–SAN, 10/04/2026: From $630
    04

    Sun

  • STL–SAN, 10/05/2026: From $630
    05

    Mon

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • STL–SAN, 10/07/2026: From $548
    07

    Wed

  • STL–SAN, 10/08/2026: From $548
    08

    Thu

  • STL–SAN, 10/09/2026: From $548
    09

    Fri

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • STL–SAN, 10/11/2026: From $548
    11

    Sun

  • STL–SAN, 10/12/2026: From $548
    12

    Mon

  • STL–SAN, 10/13/2026: From $390
    13

    Tue

  • STL–SAN, 10/14/2026: From $390
    14

    Wed

  • STL–SAN, 10/15/2026: From $390
    15

    Thu

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    16

    Fri

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • STL–SAN, 10/18/2026: From $390
    18

    Sun

  • STL–SAN, 10/19/2026: From $390
    19

    Mon

  • STL–SAN, 10/20/2026: From $390
    20

    Tue

  • STL–SAN, 10/21/2026: From $181
    21

    Wed

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

  • STL–SAN, 10/23/2026: From $210
    23

    Fri

  • STL–SAN, 10/24/2026: From $176
    24

    Sat

  • STL–SAN, 10/25/2026: From $284
    25

    Sun

  • STL–SAN, 10/26/2026: From $181
    26

    Mon

  • STL–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • STL–SAN, 10/28/2026: From $176
    28

    Wed

  • STL–SAN, 10/29/2026: From $176
    29

    Thu

    • Range$176-$630

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    San Diego International Airport
    Average flight time:
    3 hours 54 minutes
    Distance:
    1557 miles

    Route Information

    157† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from St. Louis to San Diego is 3 hours 54 minutes.
    There are 157 weekly flights from St. Louis to San Diego on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to San Diego once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to San Diego once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly St. Louis to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from St. Louis to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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