Looking for more low-fare flights?
Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.
Find low faresSouthwest® flights from St. Louis to San Francisco from $200
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Low fares from St. Louis to San Francisco
$
St. Louis (STL)to
San Francisco (SFO)
Depart: 05/12/2026
One-way
Basic
From
$200
Seen: 12 hrs ago
St. Louis (STL)to
San Francisco (SFO)
Depart: 04/14/2026
One-way
Basic
From
$200
Seen: 12 hrs ago
St. Louis (STL)to
San Francisco (SFO)
Depart: 04/08/2026
One-way
Basic
From
$200
Seen: 7 hrs ago
St. Louis (STL)to
San Francisco (SFO)
Depart: 05/07/2026
One-way
Basic
From
$200
Seen: 1 hour ago
St. Louis (STL)to
San Francisco (SFO)
Depart: 04/22/2026
One-way
Basic
From
$200
Seen: 11 hrs ago
St. Louis (STL)to
San Francisco (SFO)
Depart: 04/20/2026
One-way
Basic
From
$200
Seen: 9 hrs ago
Explore flights from St. Louis to San Francisco
location_on
location_on
Flight Details
Departing from:
Lambert-St Louis Int'l Airport
Arriving at:
San Francisco International Airport
Average flight time:
4 hours 14 minutes
Distance:
1735 miles
Route Information
153† Weekly flights
- 1‡ Nonstop flight per day Monday through Friday
- 1‡ Nonstop flight on Saturday
- 1‡ Nonstop flight on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from St. Louis to San Francisco is 4 hours 14 minutes.
There are 153 weekly flights from St. Louis to San Francisco on Southwest Airlines.
Yes, Southwest flies nonstop from St. Louis to San Francisco once per day from Monday through Friday.
Yes, Southwest flies nonstop from St. Louis to San Francisco once per day on Saturdays and Sundays.
To find the lowest fares by day and time to fly St. Louis to San Francisco with Southwest, check out our Low Fare Calendar.
You can rent a car at San Francisco International Airport book yours with your flight.
Yes! Flights from St. Louis to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.