Southwest® flights from St. Louis to San Francisco from $177

Promo Code

Low fares from St. Louis to San Francisco

$

St. Louis (STL)to

San Francisco (SFO)
Depart: 12/13/2026

One-way

Basic

From
$177
Seen: 19 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 01/28/2027

One-way

Basic

From
$177
Seen: 20 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 12/14/2026

One-way

Basic

From
$177
Seen: 16 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 01/20/2027

One-way

Basic

From
$177
Seen: 12 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 01/21/2027

One-way

Basic

From
$177
Seen: 12 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 11/11/2026

One-way

Basic

From
$177
Seen: 13 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from St. Louis to San Francisco

Oct 2026
From$528*
Seen: 21 hrs ago
One Way/Basic
Nov 2026
From$177*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$177*
Seen: 13 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $177
cmp-daily-histogram-bars-legend-max-price-aria-label $670
Displaying fares for October-2026
  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

    OCT

  • STL–SFO, 10/23/2026: From $670
    23

    Fri

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    24

    Sat

  • STL–SFO, 10/25/2026: From $670
    25

    Sun

  • STL–SFO, 10/26/2026: From $670
    26

    Mon

  • STL–SFO, 10/27/2026: From $670
    27

    Tue

  • STL–SFO, 10/28/2026: From $528
    28

    Wed

  • STL–SFO, 10/29/2026: From $528
    29

    Thu

  • STL–SFO, 10/30/2026: From $528
    30

    Fri

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • STL–SFO, 11/01/2026: From $528
    01

    Sun

    NOV

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    02

    Mon

  • STL–SFO, 11/03/2026: From $528
    03

    Tue

  • STL–SFO, 11/04/2026: From $340
    04

    Wed

  • STL–SFO, 11/05/2026: From $340
    05

    Thu

  • STL–SFO, 11/06/2026: From $340
    06

    Fri

  • STL–SFO, 11/07/2026: From $350
    07

    Sat

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • STL–SFO, 11/09/2026: From $187
    09

    Mon

  • STL–SFO, 11/10/2026: From $177
    10

    Tue

  • STL–SFO, 11/11/2026: From $177
    11

    Wed

  • STL–SFO, 11/12/2026: From $178
    12

    Thu

  • STL–SFO, 11/13/2026: From $177
    13

    Fri

  • STL–SFO, 11/14/2026: From $188
    14

    Sat

  • STL–SFO, 11/15/2026: From $187
    15

    Sun

  • STL–SFO, 11/16/2026: From $297
    16

    Mon

  • STL–SFO, 11/17/2026: From $177
    17

    Tue

  • STL–SFO, 11/18/2026: From $177
    18

    Wed

  • STL–SFO, 11/19/2026: From $187
    19

    Thu

  • STL–SFO, 11/20/2026: From $242
    20

    Fri

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

    • Range$177-$670

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    San Francisco International Airport
    Average flight time:
    4 hours 14 minutes
    Distance:
    1735 miles

    Questions we hear the most

    The average flight time from St. Louis to San Francisco is 4 hours 14 minutes.
    There are 153 weekly flights from St. Louis to San Francisco on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly St. Louis to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from St. Louis to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from St. Louis