Southwest® flights from St. Louis to San Francisco from $209

Promo Code

Low fares from St. Louis to San Francisco

$

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/29/2026

One-way

Basic

From
$209
Seen: 19 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/20/2026

One-way

Basic

From
$209
Seen: 18 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 12/02/2026

One-way

Basic

From
$209
Seen: 16 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 12/10/2026

One-way

Basic

From
$209
Seen: 22 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/27/2026

One-way

Basic

From
$209
Seen: 20 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/06/2026

One-way

Basic

From
$218
Seen: 18 hrs ago

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Explore flights from St. Louis to San Francisco

Sep 2026
From$325*
Seen: 17 hrs ago
One Way/Basic
Oct 2026
From$209*
Seen: 19 hrs ago
One Way/Basic
Nov 2026
From$219*
Seen: 17 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $218
cmp-daily-histogram-bars-legend-max-price-aria-label $670
Displaying fares for September-2026
  • STL–SFO, 09/11/2026: From $670
    11

    Fri

    SEP

  • STL–SFO, 09/12/2026: From $660
    12

    Sat

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • STL–SFO, 09/15/2026: From $660
    15

    Tue

  • STL–SFO, 09/16/2026: From $660
    16

    Wed

  • STL–SFO, 09/17/2026: From $508
    17

    Thu

  • STL–SFO, 09/18/2026: From $508
    18

    Fri

  • STL–SFO, 09/19/2026: From $508
    19

    Sat

  • STL–SFO, 09/20/2026: From $518
    20

    Sun

  • STL–SFO, 09/21/2026: From $523
    21

    Mon

  • STL–SFO, 09/22/2026: From $508
    22

    Tue

  • STL–SFO, 09/23/2026: From $508
    23

    Wed

  • STL–SFO, 09/24/2026: From $330
    24

    Thu

  • STL–SFO, 09/25/2026: From $325
    25

    Fri

  • STL–SFO, 09/26/2026: From $330
    26

    Sat

  • STL–SFO, 09/27/2026: From $330
    27

    Sun

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • STL–SFO, 09/30/2026: From $330
    30

    Wed

  • STL–SFO, 10/01/2026: From $330
    01

    Thu

    OCT

  • STL–SFO, 10/02/2026: From $249
    02

    Fri

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

  • STL–SFO, 10/04/2026: From $280
    04

    Sun

  • STL–SFO, 10/05/2026: From $219
    05

    Mon

  • STL–SFO, 10/06/2026: From $218
    06

    Tue

  • STL–SFO, 10/07/2026: From $219
    07

    Wed

  • STL–SFO, 10/08/2026: From $219
    08

    Thu

  • STL–SFO, 10/09/2026: From $259
    09

    Fri

  • STL–SFO, 10/10/2026: From $228
    10

    Sat

    • Range$218-$670

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    San Francisco International Airport
    Average flight time:
    4 hours 14 minutes
    Distance:
    1735 miles

    Route Information

    153† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from St. Louis to San Francisco is 4 hours 14 minutes.
    There are 153 weekly flights from St. Louis to San Francisco on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly St. Louis to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from St. Louis to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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