Southwest® flights from St. Louis to San Francisco from $179

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Low fares from St. Louis to San Francisco

$

St. Louis (STL)to

San Francisco (SFO)
Depart: 09/11/2026

One-way

Basic

From
$179
Seen: 15 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 09/05/2026

One-way

Basic

From
$179
Seen: 8 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/30/2026

One-way

Basic

From
$179
Seen: 10 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 09/06/2026

One-way

Basic

From
$189
Seen: 9 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/13/2026

One-way

Basic

From
$197
Seen: 17 hrs ago

St. Louis (STL)to

San Francisco (SFO)
Depart: 10/20/2026

One-way

Basic

From
$197
Seen: 22 hrs ago

Looking for more low-fare flights?

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Explore flights from St. Louis to San Francisco

Aug 2026
From$197*
Seen: 1 hour ago
One Way/Basic
Sep 2026
From$179*
Seen: 15 hrs ago
One Way/Basic
Oct 2026
From$179*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $197
cmp-daily-histogram-bars-legend-max-price-aria-label $650
Displaying fares for August-2026
  • STL–SFO, 08/03/2026: From $650
    03

    Mon

    AUG

  • STL–SFO, 08/04/2026: From $640
    04

    Tue

  • STL–SFO, 08/05/2026: From $640
    05

    Wed

  • STL–SFO, 08/06/2026: From $640
    06

    Thu

  • STL–SFO, 08/07/2026: From $640
    07

    Fri

  • STL–SFO, 08/08/2026: From $498
    08

    Sat

  • STL–SFO, 08/09/2026: From $508
    09

    Sun

  • STL–SFO, 08/10/2026: From $498
    10

    Mon

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    11

    Tue

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    12

    Wed

  • STL–SFO, 08/13/2026: From $498
    13

    Thu

  • STL–SFO, 08/14/2026: From $498
    14

    Fri

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    15

    Sat

  • STL–SFO, 08/16/2026: From $354
    16

    Sun

  • STL–SFO, 08/17/2026: From $310
    17

    Mon

  • STL–SFO, 08/18/2026: From $310
    18

    Tue

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    19

    Wed

  • STL–SFO, 08/20/2026: From $310
    20

    Thu

  • STL–SFO, 08/21/2026: From $310
    21

    Fri

  • STL–SFO, 08/22/2026: From $197
    22

    Sat

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    23

    Sun

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    24

    Mon

  • STL–SFO, 08/25/2026: From $197
    25

    Tue

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    26

    Wed

  • STL–SFO, 08/27/2026: From $207
    27

    Thu

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    28

    Fri

  • STL–SFO, 08/29/2026: From $197
    29

    Sat

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    30

    Sun

  • STL–SFO: cmp-view-offers-disclaimer. Find Offers
    31

    Mon

  • STL–SFO, 09/01/2026: From $197
    01

    Tue

    SEP

  • STL–SFO, 09/02/2026: From $197
    02

    Wed

    • Range$197-$650

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    San Francisco International Airport
    Average flight time:
    4 hours 14 minutes
    Distance:
    1735 miles

    Route Information

    153† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from St. Louis to San Francisco is 4 hours 14 minutes.
    There are 153 weekly flights from St. Louis to San Francisco on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to San Francisco once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly St. Louis to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from St. Louis to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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