Southwest® flights from St. Louis to Panama City Beach, FL from $109

Promo Code

Low fares from St. Louis to Panama City Beach, FL

$

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/28/2026

One-way

Basic

From
$109
Seen: 16 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/27/2026

One-way

Basic

From
$109
Seen: 3 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/26/2026

One-way

Basic

From
$109
Seen: 21 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/29/2026

One-way

Basic

From
$109
Seen: 21 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/31/2026

One-way

Basic

From
$109
Seen: 15 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 11/14/2026

One-way

Basic

From
$109
Seen: 10 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from St. Louis to Panama City Beach, FL

Oct 2026
From$109*
Seen: 3 hrs ago
One Way/Basic
Nov 2026
From$109*
Seen: 10 hrs ago
One Way/Basic
Dec 2026
From$114*
Seen: 17 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $109
cmp-daily-histogram-bars-legend-max-price-aria-label $470
Displaying fares for October-2026
  • STL–ECP, 10/02/2026: From $470
    02

    Fri

    OCT

  • STL–ECP, 10/03/2026: From $470
    03

    Sat

  • STL–ECP, 10/04/2026: From $470
    04

    Sun

  • STL–ECP, 10/05/2026: From $470
    05

    Mon

  • STL–ECP, 10/06/2026: From $470
    06

    Tue

  • STL–ECP, 10/07/2026: From $470
    07

    Wed

  • STL–ECP, 10/08/2026: From $330
    08

    Thu

  • STL–ECP, 10/09/2026: From $410
    09

    Fri

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    13

    Tue

  • STL–ECP, 10/14/2026: From $335
    14

    Wed

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    15

    Thu

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    16

    Fri

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • STL–ECP, 10/18/2026: From $279
    18

    Sun

  • STL–ECP, 10/19/2026: From $279
    19

    Mon

  • STL–ECP, 10/20/2026: From $279
    20

    Tue

  • STL–ECP, 10/21/2026: From $279
    21

    Wed

  • STL–ECP, 10/22/2026: From $301
    22

    Thu

  • STL–ECP, 10/23/2026: From $170
    23

    Fri

  • STL–ECP, 10/24/2026: From $114
    24

    Sat

  • STL–ECP, 10/25/2026: From $260
    25

    Sun

  • STL–ECP, 10/26/2026: From $109
    26

    Mon

  • STL–ECP, 10/27/2026: From $109
    27

    Tue

  • STL–ECP, 10/28/2026: From $109
    28

    Wed

  • STL–ECP, 10/29/2026: From $109
    29

    Thu

  • STL–ECP, 10/30/2026: From $165
    30

    Fri

  • STL–ECP, 10/31/2026: From $109
    31

    Sat

  • STL–ECP, 11/01/2026: From $238
    01

    Sun

    NOV

    • Range$109-$470

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    Northwest Florida Beaches International Airport
    Average flight time:
    1 hour 45 minutes
    Distance:
    634 miles

    Route Information

    85† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from St. Louis to Panama City Beach, FL is 1 hour 45 minutes.
    There are 85 weekly flights from St. Louis to Panama City Beach, FL on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to Panama City Beach, FL once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to Panama City Beach, FL once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly St. Louis to Panama City Beach, FL with Southwest, check out our Low Fare Calendar.
    You can rent a car at Northwest Florida Beaches International Airport book yours with your flight.
    Yes! Flights from St. Louis to Panama City Beach, FL—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from St. Louis