Southwest® flights from St. Louis to Panama City Beach, FL from $109

Promo Code

Low fares from St. Louis to Panama City Beach, FL

$

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/31/2026

One-way

Basic

From
$109
Seen: 21 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/26/2026

One-way

Basic

From
$109
Seen: 21 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/29/2026

One-way

Basic

From
$109
Seen: 21 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/27/2026

One-way

Basic

From
$109
Seen: 23 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 10/20/2026

One-way

Basic

From
$109
Seen: 14 hrs ago

St. Louis (STL)to

Panama City Beach, FL (ECP)
Depart: 11/07/2026

One-way

Basic

From
$114
Seen: 13 hrs ago

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Explore flights from St. Louis to Panama City Beach, FL

Sep 2026
From$269*
Seen: 23 hrs ago
One Way/Basic
Oct 2026
From$109*
Seen: 21 hrs ago
One Way/Basic
Nov 2026
From$114*
Seen: 13 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $187
cmp-daily-histogram-bars-legend-max-price-aria-label $470
Displaying fares for September-2026
  • STL–ECP, 09/11/2026: From $470
    11

    Fri

    SEP

  • STL–ECP, 09/12/2026: From $470
    12

    Sat

  • STL–ECP, 09/13/2026: From $460
    13

    Sun

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • STL–ECP, 09/15/2026: From $470
    15

    Tue

  • STL–ECP, 09/16/2026: From $320
    16

    Wed

  • STL–ECP, 09/17/2026: From $395
    17

    Thu

  • STL–ECP, 09/18/2026: From $330
    18

    Fri

  • STL–ECP, 09/19/2026: From $330
    19

    Sat

  • STL–ECP, 09/20/2026: From $320
    20

    Sun

  • STL–ECP, 09/21/2026: From $330
    21

    Mon

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

  • STL–ECP, 09/25/2026: From $279
    25

    Fri

  • STL–ECP, 09/26/2026: From $279
    26

    Sat

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • STL–ECP, 09/29/2026: From $269
    29

    Tue

  • STL–ECP, 09/30/2026: From $284
    30

    Wed

  • STL–ECP, 10/01/2026: From $284
    01

    Thu

    OCT

  • STL–ECP, 10/02/2026: From $197
    02

    Fri

  • STL–ECP, 10/03/2026: From $187
    03

    Sat

  • STL–ECP, 10/04/2026: From $250
    04

    Sun

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • STL–ECP: cmp-view-offers-disclaimer. Find Offers
    07

    Wed

  • STL–ECP, 10/08/2026: From $296
    08

    Thu

  • STL–ECP, 10/09/2026: From $313
    09

    Fri

  • STL–ECP, 10/10/2026: From $197
    10

    Sat

    • Range$187-$470

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    Northwest Florida Beaches International Airport
    Average flight time:
    1 hour 45 minutes
    Distance:
    634 miles

    Route Information

    85† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from St. Louis to Panama City Beach, FL is 1 hour 45 minutes.
    There are 85 weekly flights from St. Louis to Panama City Beach, FL on Southwest Airlines.
    Yes, Southwest flies nonstop from St. Louis to Panama City Beach, FL once per day from Monday through Friday.
    Yes, Southwest flies nonstop from St. Louis to Panama City Beach, FL once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly St. Louis to Panama City Beach, FL with Southwest, check out our Low Fare Calendar.
    You can rent a car at Northwest Florida Beaches International Airport book yours with your flight.
    Yes! Flights from St. Louis to Panama City Beach, FL—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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