Southwest® flights from St. Louis to Orange County/Santa Ana from $200

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Low fares from St. Louis to Orange County/Santa Ana

$

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 11/12/2026

One-way

Basic

From
$200
Seen: 20 hrs ago

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 10/03/2026

One-way

Basic

From
$200
Seen: 4 hrs ago

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 12/17/2026

One-way

Basic

From
$200
Seen: 22 hrs ago

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 11/05/2026

One-way

Basic

From
$200
Seen: 21 hrs ago

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 11/04/2026

One-way

Basic

From
$200
Seen: 23 hrs ago

St. Louis (STL)to

Orange County/Santa Ana (SNA)
Depart: 12/16/2026

One-way

Basic

From
$200
Seen: 23 hrs ago

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Explore flights from St. Louis to Orange County/Santa Ana

Sep 2026
From$289*
Seen: 8 hrs ago
One Way/Basic
Oct 2026
From$200*
Seen: 4 hrs ago
One Way/Basic
Nov 2026
From$200*
Seen: 19 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $200
cmp-daily-histogram-bars-legend-max-price-aria-label $614
Displaying fares for September-2026
  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

    SEP

  • STL–SNA, 09/12/2026: From $614
    12

    Sat

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • STL–SNA, 09/16/2026: From $614
    16

    Wed

  • STL–SNA, 09/17/2026: From $614
    17

    Thu

  • STL–SNA, 09/18/2026: From $514
    18

    Fri

  • STL–SNA, 09/19/2026: From $514
    19

    Sat

  • STL–SNA, 09/20/2026: From $524
    20

    Sun

  • STL–SNA, 09/21/2026: From $509
    21

    Mon

  • STL–SNA, 09/22/2026: From $524
    22

    Tue

  • STL–SNA, 09/23/2026: From $294
    23

    Wed

  • STL–SNA, 09/24/2026: From $294
    24

    Thu

  • STL–SNA, 09/25/2026: From $304
    25

    Fri

  • STL–SNA, 09/26/2026: From $294
    26

    Sat

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • STL–SNA, 09/28/2026: From $289
    28

    Mon

  • STL–SNA, 09/29/2026: From $294
    29

    Tue

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • STL–SNA, 10/01/2026: From $304
    01

    Thu

    OCT

  • STL–SNA, 10/02/2026: From $242
    02

    Fri

  • STL–SNA, 10/03/2026: From $200
    03

    Sat

  • STL–SNA, 10/04/2026: From $280
    04

    Sun

  • STL–SNA, 10/05/2026: From $242
    05

    Mon

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • STL–SNA, 10/07/2026: From $242
    07

    Wed

  • STL–SNA, 10/08/2026: From $242
    08

    Thu

  • STL–SNA, 10/09/2026: From $270
    09

    Fri

  • STL–SNA: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

    • Range$200-$614

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    John Wayne Airport
    Distance:
    1569 miles

    Route Information

    152† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 152 weekly flights from St. Louis to Orange County/Santa Ana on Southwest Airlines.
    To find the lowest fares by day and time to fly St. Louis to Orange County/Santa Ana with Southwest, check out our Low Fare Calendar.
    You can rent a car at John Wayne Airport book yours with your flight.
    Yes! Flights from St. Louis to Orange County/Santa Ana—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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