Southwest® flights from Buffalo/Niagara Falls to Panama City Beach, FL from $339

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Low fares from Buffalo/Niagara Falls to Panama City Beach, FL

$

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 11/06/2026

One-way

Basic

From
$339
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 10/21/2026

One-way

Choice

From
$351
Seen: 7 hrs ago

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 10/27/2026

One-way

Choice

From
$351
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 11/06/2026

One-way

Choice

From
$375
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 10/27/2026

One-way

Choice Preferred

From
$421
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Panama City Beach, FL (ECP)
Depart: 10/21/2026

One-way

Choice Preferred

From
$421
Seen: 7 hrs ago

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Explore flights from Buffalo/Niagara Falls to Panama City Beach, FL

Oct 2026
From$351*
Seen: 7 hrs ago
One Way/Basic
Nov 2026
From$339*
Seen: 15 hrs ago
One Way/Basic
Dec 2026
No result for this month.
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Displaying fares for October-2026
  • BUF–ECP, 10/21/2026: From $351
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  • BUF–ECP, 10/22/2026: From $436
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  • BUF–ECP, 10/27/2026: From $351
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  • BUF–ECP, 11/06/2026: From $339
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    • Range$339-$436

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Northwest Florida Beaches International Airport
    Distance:
    951 miles

    Questions we hear the most

    There are 43 weekly flights from Buffalo/Niagara Falls to Panama City Beach, FL on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Panama City Beach, FL with Southwest, check out our Low Fare Calendar.
    You can rent a car at Northwest Florida Beaches International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Panama City Beach, FL—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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