Southwest® flights from Orlando to Knoxville from $124

Promo Code

Low fares from Orlando to Knoxville

$

Orlando (MCO)to

Knoxville (TYS)
Depart: 11/12/2026

One-way

Basic

From
$124

Low fares from Orlando to Knoxville

$

Orlando (MCO)to

Knoxville (TYS)
Depart: 11/12/2026

One-way

Basic

From
$124
Seen: 8 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 12/14/2026

One-way

Basic

From
$124
Seen: 15 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 11/11/2026

One-way

Basic

From
$124
Seen: 5 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 11/13/2026

One-way

Basic

From
$124
Seen: 15 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 11/02/2026

One-way

Basic

From
$124
Seen: 19 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 10/31/2026

One-way

Basic

From
$124
Seen: 18 hrs ago

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Explore flights from Orlando to Knoxville

Oct 2026
From$124*
Seen: 18 hrs ago
One Way/Basic
Nov 2026
From$124*
Seen: 5 hrs ago
One Way/Basic
Dec 2026
From$124*
Seen: 15 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $124
cmp-daily-histogram-bars-legend-max-price-aria-label $477
Displaying fares for October-2026
  • MCO–TYS, 10/03/2026: From $304
    03

    Sat

    OCT

  • MCO–TYS, 10/04/2026: From $304
    04

    Sun

  • MCO–TYS, 10/05/2026: From $304
    05

    Mon

  • MCO–TYS, 10/06/2026: From $477
    06

    Tue

  • MCO–TYS, 10/07/2026: From $304
    07

    Wed

  • MCO–TYS, 10/08/2026: From $314
    08

    Thu

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    09

    Fri

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • MCO–TYS, 10/11/2026: From $314
    11

    Sun

  • MCO–TYS, 10/12/2026: From $259
    12

    Mon

  • MCO–TYS, 10/13/2026: From $259
    13

    Tue

  • MCO–TYS, 10/14/2026: From $259
    14

    Wed

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    15

    Thu

  • MCO–TYS, 10/16/2026: From $385
    16

    Fri

  • MCO–TYS, 10/17/2026: From $209
    17

    Sat

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    18

    Sun

  • MCO–TYS, 10/19/2026: From $184
    19

    Mon

  • MCO–TYS, 10/20/2026: From $184
    20

    Tue

  • MCO–TYS, 10/21/2026: From $184
    21

    Wed

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

  • MCO–TYS, 10/23/2026: From $271
    23

    Fri

  • MCO–TYS, 10/24/2026: From $129
    24

    Sat

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • MCO–TYS, 10/26/2026: From $154
    26

    Mon

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    30

    Fri

  • MCO–TYS, 10/31/2026: From $124
    31

    Sat

  • MCO–TYS: cmp-view-offers-disclaimer. Find Offers
    01

    Sun

    NOV

  • MCO–TYS, 11/02/2026: From $124
    02

    Mon

    • Range$124-$477

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Orlando International Airport
    Arriving at:
    Mc Ghee Tyson Airport
    Average flight time:
    1 hour 45 minutes
    Distance:
    532 miles

    Route Information

    67† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Orlando to Knoxville is 1 hour 45 minutes.
    There are 67 weekly flights from Orlando to Knoxville on Southwest Airlines.
    Yes, Southwest flies nonstop from Orlando to Knoxville once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Orlando to Knoxville once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Orlando to Knoxville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Mc Ghee Tyson Airport book yours with your flight.
    Yes! Flights from Orlando to Knoxville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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