Southwest® flights from St. Louis to Louisville from $149

Promo Code

Low fares from St. Louis to Louisville

$

St. Louis (STL)to

Louisville (SDF)
Depart: 10/15/2026

One-way

Basic

From
$149
Seen: 9 hrs ago

St. Louis (STL)to

Louisville (SDF)
Depart: 10/22/2026

One-way

Basic

From
$149
Seen: 4 hrs ago

St. Louis (STL)to

Louisville (SDF)
Depart: 10/12/2026

One-way

Basic

From
$149
Seen: 10 hrs ago

St. Louis (STL)to

Louisville (SDF)
Depart: 10/05/2026

One-way

Basic

From
$149
Seen: 18 hrs ago

St. Louis (STL)to

Louisville (SDF)
Depart: 10/17/2026

One-way

Basic

From
$160
Seen: 21 minutes ago

St. Louis (STL)to

Louisville (SDF)
Depart: 10/23/2026

One-way

Basic

From
$160
Seen: 7 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from St. Louis to Louisville

Sep 2026
From$265*
Seen: 9 hrs ago
One Way/Basic
Oct 2026
From$149*
Seen: 10 hrs ago
One Way/Basic
Nov 2026
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $149
cmp-daily-histogram-bars-legend-max-price-aria-label $446
Displaying fares for September-2026
  • STL–SDF, 09/11/2026: From $406
    11

    Fri

    SEP

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • STL–SDF, 09/13/2026: From $446
    13

    Sun

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • STL–SDF, 09/16/2026: From $446
    16

    Wed

  • STL–SDF, 09/17/2026: From $348
    17

    Thu

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • STL–SDF, 09/20/2026: From $348
    20

    Sun

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • STL–SDF, 09/23/2026: From $293
    23

    Wed

  • STL–SDF, 09/24/2026: From $342
    24

    Thu

  • STL–SDF, 09/25/2026: From $265
    25

    Fri

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    26

    Sat

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    01

    Thu

    OCT

  • STL–SDF, 10/02/2026: From $160
    02

    Fri

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • STL–SDF, 10/05/2026: From $149
    05

    Mon

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    07

    Wed

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    08

    Thu

  • STL–SDF, 10/09/2026: From $293
    09

    Fri

  • STL–SDF: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

    • Range$149-$446

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Lambert-St Louis Int'l Airport
    Arriving at:
    Louisville International Airport
    Distance:
    254 miles

    Route Information

    148† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 148 weekly flights from St. Louis to Louisville on Southwest Airlines.
    To find the lowest fares by day and time to fly St. Louis to Louisville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Louisville International Airport book yours with your flight.
    Yes! Flights from St. Louis to Louisville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from St. Louis