Southwest® flights from Portland, ME to San Antonio from $184

Promo Code

Low fares from Portland, ME to San Antonio

$

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 05/07/2026

One-way

Basic

From
$184
Seen: 22 hrs ago

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 05/20/2026

One-way

Basic

From
$184
Seen: 1 hour ago

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 05/21/2026

One-way

Basic

From
$220
Seen: 9 hrs ago

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 04/10/2026

One-way

Basic

From
$220
Seen: 3 hrs ago

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 05/07/2026

One-way

Choice

From
$224
Seen: 22 hrs ago

Portland, ME (PWM)to

San Antonio (SAT)
Depart: 05/20/2026

One-way

Choice

From
$224
Seen: 1 hour ago

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Explore flights from Portland, ME to San Antonio

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Portland International Jetport
Arriving at:
San Antonio International Airport
Distance:
1830 miles

Route Information

71† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 71 weekly flights from Portland, ME to San Antonio on Southwest Airlines.
To find the lowest fares by day and time to fly Portland, ME to San Antonio with Southwest, check out our Low Fare Calendar.
You can rent a car at San Antonio International Airport book yours with your flight.
Yes! Flights from Portland, ME to San Antonio—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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