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Find low faresSouthwest® flights from Portland, ME to New Orleans from $149
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Low fares from Portland, ME to New Orleans
$
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 03/03/2026
One-way
Basic
From
$149
Seen: 15 hrs ago
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 03/11/2026
One-way
Basic
From
$184
Seen: 52 minutes ago
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 03/03/2026
One-way
Choice
From
$189
Seen: 15 hrs ago
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 04/27/2026
One-way
Basic
From
$189
Seen: 5 hrs ago
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 03/09/2026
One-way
Basic
From
$214
Seen: 1 hour ago
Portland, ME (PWM)to
New Orleans (MSY)
Depart: 03/13/2026
One-way
Basic
From
$214
Seen: 6 hrs ago
Explore flights from Portland, ME to New Orleans
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Flight Details
Departing from:
Portland International Jetport
Arriving at:
Louis Armstrong International Airport
Distance:
1446 miles
Route Information
73† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 73 weekly flights from Portland, ME to New Orleans on Southwest Airlines.
To find the lowest fares by day and time to fly Portland, ME to New Orleans with Southwest, check out our Low Fare Calendar.
You can rent a car at Louis Armstrong International Airport book yours with your flight.
Yes! Flights from Portland, ME to New Orleans—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.