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Find low faresSouthwest® flights from St. Louis to Myrtle Beach from $132
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1 Passenger
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Low fares from St. Louis to Myrtle Beach
$
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 04/11/2026
One-way
Basic
From
$132
Seen: 2 hrs ago
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 05/02/2026
One-way
Basic
From
$132
Seen: 2 hrs ago
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 03/28/2026
One-way
Basic
From
$132
Seen: 3 hrs ago
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 02/28/2026
One-way
Basic
From
$142
Seen: 2 hrs ago
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 04/18/2026
One-way
Basic
From
$160
Seen: 1 hour ago
St. Louis (STL)to
Myrtle Beach (MYR)
Depart: 03/28/2026
One-way
Choice
From
$167
Seen: 3 hrs ago
Explore flights from St. Louis to Myrtle Beach
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Flight Details
Departing from:
Lambert-St Louis Int'l Airport
Arriving at:
Myrtle Beach International Airport
Average flight time:
1 hour 50 minutes
Distance:
728 miles
Route Information
87† Weekly flights
- 1‡ Nonstop flight on Saturday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from St. Louis to Myrtle Beach is 1 hour 50 minutes.
There are 87 weekly flights from St. Louis to Myrtle Beach on Southwest Airlines.
Yes, Southwest flies nonstop from St. Louis to Myrtle Beach once per day on Saturdays.
To find the lowest fares by day and time to fly St. Louis to Myrtle Beach with Southwest, check out our Low Fare Calendar.
You can rent a car at Myrtle Beach International Airport book yours with your flight.
Yes! Flights from St. Louis to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.