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Find low faresSouthwest® flights from St. Louis to Rochester from $161
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1 Passenger
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Low fares from St. Louis to Rochester
$
St. Louis (STL)to
Rochester (ROC)
Depart: 03/17/2026
One-way
Basic
From
$161
Seen: 18 hrs ago
St. Louis (STL)to
Rochester (ROC)
Depart: 04/30/2026
One-way
Basic
From
$161
Seen: 8 hrs ago
St. Louis (STL)to
Rochester (ROC)
Depart: 02/28/2026
One-way
Basic
From
$166
Seen: 19 hrs ago
St. Louis (STL)to
Rochester (ROC)
Depart: 02/18/2026
One-way
Basic
From
$170
Seen: 7 hrs ago
St. Louis (STL)to
Rochester (ROC)
Depart: 02/27/2026
One-way
Basic
From
$175
Seen: 19 hrs ago
St. Louis (STL)to
Rochester (ROC)
Depart: 05/07/2026
One-way
Basic
From
$184
Seen: 5 hrs ago
Explore flights from St. Louis to Rochester
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Flight Details
Departing from:
Lambert-St Louis Int'l Airport
Arriving at:
Greater Rochester International Airport
Distance:
729 miles
Route Information
76† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 76 weekly flights from St. Louis to Rochester on Southwest Airlines.
To find the lowest fares by day and time to fly St. Louis to Rochester with Southwest, check out our Low Fare Calendar.
You can rent a car at Greater Rochester International Airport book yours with your flight.
Yes! Flights from St. Louis to Rochester—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.