Southwest® flights from Detroit to Portland, ME from $255

Promo Code

Low fares from Detroit to Portland, ME

$

Detroit (DTW)to

Portland, ME (PWM)
Depart: 04/21/2026

One-way

Basic

From
$255
Seen: 1 hour ago

Detroit (DTW)to

Portland, ME (PWM)
Depart: 04/21/2026

One-way

Choice

From
$290
Seen: 1 hour ago

Detroit (DTW)to

Portland, ME (PWM)
Depart: 03/23/2026

One-way

Basic

From
$330
Seen: 6 hrs ago

Detroit (DTW)to

Portland, ME (PWM)
Depart: 03/23/2026

One-way

Choice

From
$350
Seen: 6 hrs ago

Detroit (DTW)to

Portland, ME (PWM)
Depart: 04/21/2026

One-way

Choice Preferred

From
$360
Seen: 1 hour ago

Detroit (DTW)to

Portland, ME (PWM)
Depart: 03/27/2026

One-way

Choice

From
$395
Seen: 19 hrs ago

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Explore flights from Detroit to Portland, ME

Mar 2026
From$330*
Seen: 6 hrs ago
One Way/Basic
Apr 2026
From$255*
Seen: 1 hour ago
One Way/Basic
May 2026
No result for this month.
$330
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    • Range$330-$395

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Wayne County Airport
    Arriving at:
    Portland International Jetport
    Distance:
    668 miles

    Route Information

    66† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 66 weekly flights from Detroit to Portland, ME on Southwest Airlines.
    To find the lowest fares by day and time to fly Detroit to Portland, ME with Southwest, check out our Low Fare Calendar.
    You can rent a car at Portland International Jetport book yours with your flight.
    Yes! Flights from Detroit to Portland, ME—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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