Southwest® flights from Myrtle Beach to Columbus from $152

Promo Code

Low fares from Myrtle Beach to Columbus

$

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 12/12/2026

One-way

Basic

From
$152
Seen: 22 hrs ago

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 12/14/2026

One-way

Basic

From
$167
Seen: 8 hrs ago

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 12/21/2026

One-way

Basic

From
$167
Seen: 4 hrs ago

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 12/07/2026

One-way

Basic

From
$177
Seen: 27 minutes ago

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 02/12/2027

One-way

Basic

From
$177
Seen: 23 hrs ago

Myrtle Beach (MYR)to

Columbus (CMH)
Depart: 12/12/2026

One-way

Choice

From
$187
Seen: 22 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Myrtle Beach to Columbus

Nov 2026
From$237*
Seen: 3 hrs ago
One Way/Basic
Dec 2026
From$152*
Seen: 22 hrs ago
One Way/Basic
Jan 2027
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $177
cmp-daily-histogram-bars-legend-max-price-aria-label $364
Displaying fares for November-2026
  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

    NOV

  • MYR–CMH, 11/12/2026: From $295
    12

    Thu

  • MYR–CMH, 11/13/2026: From $295
    13

    Fri

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • MYR–CMH, 11/19/2026: From $295
    19

    Thu

  • MYR–CMH, 11/20/2026: From $295
    20

    Fri

  • MYR–CMH, 11/21/2026: From $295
    21

    Sat

  • MYR–CMH, 11/22/2026: From $338
    22

    Sun

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • MYR–CMH, 11/24/2026: From $237
    24

    Tue

  • MYR–CMH, 11/25/2026: From $237
    25

    Wed

  • MYR–CMH, 11/26/2026: From $237
    26

    Thu

  • MYR–CMH, 11/27/2026: From $364
    27

    Fri

  • MYR–CMH, 11/28/2026: From $295
    28

    Sat

  • MYR–CMH, 11/29/2026: From $319
    29

    Sun

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • MYR–CMH, 12/07/2026: From $177
    07

    Mon

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • MYR–CMH: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

    • Range$177-$364

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Myrtle Beach International Airport
    Arriving at:
    Port Columbus International Airport
    Distance:
    488 miles

    Questions we hear the most

    There are 79 weekly flights from Myrtle Beach to Columbus on Southwest Airlines.
    To find the lowest fares by day and time to fly Myrtle Beach to Columbus with Southwest, check out our Low Fare Calendar.
    You can rent a car at Port Columbus International Airport book yours with your flight.
    Yes! Flights from Myrtle Beach to Columbus—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Myrtle Beach