Southwest® flights from Myrtle Beach to Minneapolis/St. Paul from $160

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Low fares from Myrtle Beach to Minneapolis/St. Paul

$

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 05/13/2026

One-way

Basic

From
$160
Seen: 3 hrs ago

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 04/30/2026

One-way

Basic

From
$189
Seen: 17 hrs ago

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 05/13/2026

One-way

Choice

From
$200
Seen: 3 hrs ago

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 05/01/2026

One-way

Basic

From
$210
Seen: 17 hrs ago

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 04/30/2026

One-way

Choice

From
$229
Seen: 17 hrs ago

Myrtle Beach (MYR)to

Minneapolis/St. Paul (MSP)
Depart: 05/17/2026

One-way

Basic

From
$229
Seen: 16 hrs ago

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Find low fares

Explore flights from Myrtle Beach to Minneapolis/St. Paul

Mar 2026
From$380*
Seen: 4 hrs ago
One Way/Basic
Apr 2026
From$189*
Seen: 17 hrs ago
One Way/Basic
May 2026
From$160*
Seen: 3 hrs ago
One Way/Basic
$380
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    • Range$380-$489

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Myrtle Beach International Airport
    Arriving at:
    Minneapolis-St Paul International Airport
    Distance:
    1085 miles

    Route Information

    59† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 59 weekly flights from Myrtle Beach to Minneapolis/St. Paul on Southwest Airlines.
    To find the lowest fares by day and time to fly Myrtle Beach to Minneapolis/St. Paul with Southwest, check out our Low Fare Calendar.
    You can rent a car at Minneapolis-St Paul International Airport book yours with your flight.
    Yes! Flights from Myrtle Beach to Minneapolis/St. Paul—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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