Southwest® flights from Knoxville to Pittsburgh from $120

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Low fares from Knoxville to Pittsburgh

$

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 11/26/2026

One-way

Basic

From
$120

Low fares from Knoxville to Pittsburgh

$

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 11/26/2026

One-way

Basic

From
$120
Seen: 19 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 12/09/2026

One-way

Basic

From
$120
Seen: 23 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 11/21/2026

One-way

Basic

From
$120
Seen: 13 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 02/05/2027

One-way

Basic

From
$144
Seen: 18 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 12/09/2026

One-way

Choice

From
$155
Seen: 23 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 11/26/2026

One-way

Choice

From
$155
Seen: 19 hrs ago

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Explore flights from Knoxville to Pittsburgh

Oct 2026
From$346*
Seen: 21 hrs ago
One Way/Basic
Nov 2026
From$120*
Seen: 19 hrs ago
One Way/Basic
Dec 2026
From$120*
Seen: 23 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $120
cmp-daily-histogram-bars-legend-max-price-aria-label $346
Displaying fares for October-2026
  • TYS–PIT, 10/29/2026: From $346
    29

    Thu

    OCT

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    30

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    31

    Sat

  • TYS–PIT, 11/01/2026: From $346
    01

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    NOV

  • TYS–PIT, 11/02/2026: From $346
    02

    Mon

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    03

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    04

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    05

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    06

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    07

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    08

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    09

    Mon

  • TYS–PIT, 11/10/2026: From $255
    10

    Tue

  • TYS–PIT, 11/11/2026: From $253
    11

    Wed

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    12

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    13

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    14

    Sat

  • TYS–PIT, 11/15/2026: From $244
    15

    Sun

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    16

    Mon

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    17

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    18

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    19

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    20

    Fri

  • TYS–PIT, 11/21/2026: From $120
    21

    Sat

  • TYS–PIT, 11/22/2026: From $249
    22

    Sun

  • TYS–PIT, 11/23/2026: From $214
    23

    Mon

  • TYS–PIT, 11/24/2026: From $264
    24

    Tue

  • TYS–PIT, 11/25/2026: From $233
    25

    Wed

  • TYS–PIT, 11/26/2026: From $120
    26

    Thu

  • TYS–PIT, 11/27/2026: From $214
    27

    Fri

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    28

    Sat

    • Range$120-$346

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Pittsburgh International Airport
    Distance:
    382 miles

    Questions we hear the most

    There are 53 weekly flights from Knoxville to Pittsburgh on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Pittsburgh with Southwest, check out our Low Fare Calendar.
    You can rent a car at Pittsburgh International Airport book yours with your flight.
    Yes! Flights from Knoxville to Pittsburgh—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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