Southwest® flights from Knoxville to Pittsburgh from $133

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Low fares from Knoxville to Pittsburgh

$

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 10/31/2026

One-way

Basic

From
$133

Low fares from Knoxville to Pittsburgh

$

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 07/28/2026

One-way

Basic

From
$133
Seen: 9 minutes ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 08/20/2026

One-way

Basic

From
$145
Seen: 8 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 07/28/2026

One-way

Choice

From
$168
Seen: 9 minutes ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 08/20/2026

One-way

Choice

From
$180
Seen: 8 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 10/03/2026

One-way

Basic

From
$188
Seen: 4 hrs ago

Knoxville (TYS)to

Pittsburgh (PIT)
Depart: 07/23/2026

One-way

Basic

From
$189
Seen: 7 hrs ago

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Explore flights from Knoxville to Pittsburgh

Jun 2026
From$230*
Seen: 15 hrs ago
One Way/Basic
Jul 2026
From$133*
Seen: 9 minutes ago
One Way/Basic
Aug 2026
From$145*
Seen: 8 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $133
cmp-daily-histogram-bars-legend-max-price-aria-label $331
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    • Range$133-$331

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Pittsburgh International Airport
    Distance:
    382 miles

    Route Information

    53† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 53 weekly flights from Knoxville to Pittsburgh on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Pittsburgh with Southwest, check out our Low Fare Calendar.
    You can rent a car at Pittsburgh International Airport book yours with your flight.
    Yes! Flights from Knoxville to Pittsburgh—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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