Southwest® flights from Knoxville to Harlingen/South Padre Island from $259

Promo Code

Low fares from Knoxville to Harlingen/South Padre Island

$

Knoxville (TYS)to

Harlingen/South Padre Island (HRL)
Depart: 11/23/2026

One-way

Basic

From
$259

Low fares from Knoxville to Harlingen/South Padre Island

$

Knoxville (TYS)to

Harlingen/South Padre Island (HRL)
Depart: 11/23/2026

One-way

Basic

From
$259
Seen: 15 hrs ago

Knoxville (TYS)to

Harlingen/South Padre Island (HRL)
Depart: 11/23/2026

One-way

Choice

From
$304
Seen: 15 hrs ago

Knoxville (TYS)to

Harlingen/South Padre Island (HRL)
Depart: 11/23/2026

One-way

Choice Preferred

From
$384
Seen: 15 hrs ago

Knoxville (TYS)to

Harlingen/South Padre Island (HRL)
Depart: 11/23/2026

One-way

Choice Extra

From
$444
Seen: 15 hrs ago

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Explore flights from Knoxville to Harlingen/South Padre Island

Try alternate month or interact with individual days below in order to find offers.
Oct 2026
No result for this month.
Nov 2026
From$259*
Seen: 15 hrs ago
One Way/Basic
Dec 2026
No result for this month.
Displaying fares for October-2026
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    • *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Valley International Airport
    Distance:
    1043 miles

    Questions we hear the most

    There are 29 weekly flights from Knoxville to Harlingen/South Padre Island on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Harlingen/South Padre Island with Southwest, check out our Low Fare Calendar.
    You can rent a car at Valley International Airport book yours with your flight.
    Yes! Flights from Knoxville to Harlingen/South Padre Island—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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