Southwest® flights from Knoxville to Charleston from $120

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Low fares from Knoxville to Charleston

$

Knoxville (TYS)to

Charleston (CHS)
Depart: 11/25/2026

One-way

Basic

From
$120

Low fares from Knoxville to Charleston

$

Knoxville (TYS)to

Charleston (CHS)
Depart: 11/25/2026

One-way

Basic

From
$120
Seen: 16 hrs ago

Knoxville (TYS)to

Charleston (CHS)
Depart: 11/10/2026

One-way

Basic

From
$120
Seen: 7 hrs ago

Knoxville (TYS)to

Charleston (CHS)
Depart: 10/28/2026

One-way

Basic

From
$125
Seen: 21 hrs ago

Knoxville (TYS)to

Charleston (CHS)
Depart: 11/25/2026

One-way

Choice

From
$158
Seen: 16 hrs ago

Knoxville (TYS)to

Charleston (CHS)
Depart: 11/10/2026

One-way

Choice

From
$158
Seen: 7 hrs ago

Knoxville (TYS)to

Charleston (CHS)
Depart: 10/28/2026

One-way

Choice

From
$163
Seen: 21 hrs ago

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Explore flights from Knoxville to Charleston

Oct 2026
From$125*
Seen: 21 hrs ago
One Way/Basic
Nov 2026
From$120*
Seen: 7 hrs ago
One Way/Basic
Dec 2026
From$239*
Seen: 7 hrs ago
One Way/Basic
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  • TYS–CHS, 10/15/2026: From $304
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  • TYS–CHS, 10/18/2026: From $504
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  • TYS–CHS, 10/28/2026: From $125
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    NOV

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    • Range$125-$504

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Charleston International Airport
    Distance:
    302 miles

    Questions we hear the most

    There are 39 weekly flights from Knoxville to Charleston on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Charleston with Southwest, check out our Low Fare Calendar.
    You can rent a car at Charleston International Airport book yours with your flight.
    Yes! Flights from Knoxville to Charleston—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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