Southwest® flights from Knoxville to Minneapolis/St. Paul from $167

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Low fares from Knoxville to Minneapolis/St. Paul

$

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/01/2026

One-way

Basic

From
$167

Low fares from Knoxville to Minneapolis/St. Paul

$

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/17/2026

One-way

Basic

From
$167
Seen: 11 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/01/2026

One-way

Basic

From
$167
Seen: 12 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/03/2026

One-way

Basic

From
$167
Seen: 9 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/16/2026

One-way

Basic

From
$167
Seen: 16 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 12/02/2026

One-way

Basic

From
$167
Seen: 15 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 11/26/2026

One-way

Basic

From
$178
Seen: 10 hrs ago
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Explore flights from Knoxville to Minneapolis/St. Paul

cmp-daily-histogram-bars-legend-min-price-aria-label $167
cmp-daily-histogram-bars-legend-max-price-aria-label $527
Displaying fares for November-2026
  • TYS–MSP, 11/02/2026: From $330
    02

    Mon

    NOV

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    04

    Wed

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    05

    Thu

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • TYS–MSP, 11/08/2026: From $527
    08

    Sun

  • TYS–MSP, 11/09/2026: From $280
    09

    Mon

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    10

    Tue

  • TYS–MSP, 11/11/2026: From $280
    11

    Wed

  • TYS–MSP, 11/12/2026: From $280
    12

    Thu

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • TYS–MSP, 11/14/2026: From $280
    14

    Sat

  • TYS–MSP: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • TYS–MSP, 11/16/2026: From $250
    16

    Mon

  • TYS–MSP, 11/17/2026: From $250
    17

    Tue

  • TYS–MSP, 11/18/2026: From $250
    18

    Wed

  • TYS–MSP, 11/19/2026: From $250
    19

    Thu

  • TYS–MSP, 11/20/2026: From $250
    20

    Fri

  • TYS–MSP, 11/21/2026: From $250
    21

    Sat

  • TYS–MSP, 11/22/2026: From $314
    22

    Sun

  • TYS–MSP, 11/23/2026: From $230
    23

    Mon

  • TYS–MSP, 11/24/2026: From $314
    24

    Tue

  • TYS–MSP, 11/25/2026: From $274
    25

    Wed

  • TYS–MSP, 11/26/2026: From $178
    26

    Thu

  • TYS–MSP, 11/27/2026: From $230
    27

    Fri

  • TYS–MSP, 11/28/2026: From $335
    28

    Sat

  • TYS–MSP, 11/29/2026: From $504
    29

    Sun

  • TYS–MSP, 11/30/2026: From $280
    30

    Mon

  • TYS–MSP, 12/01/2026: From $167
    01

    Tue

    DEC

  • Range$167-$527

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Minneapolis-St Paul International Airport
    Distance:
    792 miles

    Questions we hear the most

    There are 43 weekly flights from Knoxville to Minneapolis/St. Paul on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Minneapolis/St. Paul with Southwest, check out our Low Fare Calendar.
    You can rent a car at Minneapolis-St Paul International Airport book yours with your flight.
    Yes! Flights from Knoxville to Minneapolis/St. Paul—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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