Southwest® flights from Knoxville to Minneapolis/St. Paul from $167

Promo Code

Low fares from Knoxville to Minneapolis/St. Paul

$

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 10/21/2026

One-way

Basic

From
$167

Low fares from Knoxville to Minneapolis/St. Paul

$

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 10/21/2026

One-way

Basic

From
$167
Seen: 23 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 11/04/2026

One-way

Basic

From
$167
Seen: 14 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 11/11/2026

One-way

Basic

From
$167
Seen: 1 hour ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 10/26/2026

One-way

Basic

From
$190
Seen: 18 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 10/21/2026

One-way

Choice

From
$207
Seen: 23 hrs ago

Knoxville (TYS)to

Minneapolis/St. Paul (MSP)
Depart: 11/11/2026

One-way

Choice

From
$207
Seen: 1 hour ago

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Explore flights from Knoxville to Minneapolis/St. Paul

Sep 2026
From$254*
Seen: 4 hrs ago
One Way/Basic
Oct 2026
From$167*
Seen: 23 hrs ago
One Way/Basic
Nov 2026
From$167*
Seen: 14 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $167
Displaying fares for September-2026
  • TYS–MSP, 09/22/2026: From $254
    22

    Tue

    SEP

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    23

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    24

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    25

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    26

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    27

    Sun

  • TYS–MSP, 09/28/2026: From $433
    28

    Mon

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    29

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    30

    Wed

  • TYS–MSP, 10/01/2026: From $270
    01

    Thu

    OCT

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    02

    Fri

  • TYS–MSP, 10/03/2026: From $400
    03

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    04

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    05

    Mon

  • TYS–MSP, 10/06/2026: From $240
    06

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  • TYS–MSP, 10/07/2026: From $240
    07

    Wed

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    08

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    09

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    10

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  • TYS–MSP, 10/11/2026: From $240
    11

    Sun

  • TYS–MSP, 10/12/2026: From $270
    12

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    13

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    14

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    15

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    16

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    17

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    18

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    19

    Mon

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    20

    Tue

  • TYS–MSP, 10/21/2026: From $167
    21

    Wed

    • Range$167-$433

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Minneapolis-St Paul International Airport
    Distance:
    792 miles

    Route Information

    43† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 43 weekly flights from Knoxville to Minneapolis/St. Paul on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Minneapolis/St. Paul with Southwest, check out our Low Fare Calendar.
    You can rent a car at Minneapolis-St Paul International Airport book yours with your flight.
    Yes! Flights from Knoxville to Minneapolis/St. Paul—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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