Southwest® flights from Knoxville to Phoenix from $160

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Low fares from Knoxville to Phoenix

$

Knoxville (TYS)to

Phoenix (PHX)
Depart: 12/02/2026

One-way

Basic

From
$160

Low fares from Knoxville to Phoenix

$

Knoxville (TYS)to

Phoenix (PHX)
Depart: 12/02/2026

One-way

Basic

From
$160
Seen: 22 hrs ago

Knoxville (TYS)to

Phoenix (PHX)
Depart: 11/05/2026

One-way

Basic

From
$160
Seen: 20 hrs ago

Knoxville (TYS)to

Phoenix (PHX)
Depart: 12/09/2026

One-way

Basic

From
$160
Seen: 6 hrs ago

Knoxville (TYS)to

Phoenix (PHX)
Depart: 10/28/2026

One-way

Basic

From
$160
Seen: 6 hrs ago

Knoxville (TYS)to

Phoenix (PHX)
Depart: 11/06/2026

One-way

Basic

From
$195
Seen: 5 hrs ago

Knoxville (TYS)to

Phoenix (PHX)
Depart: 11/13/2026

One-way

Basic

From
$195
Seen: 4 minutes ago

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Explore flights from Knoxville to Phoenix

Sep 2026
From$300*
Seen: 7 hrs ago
One Way/Basic
Oct 2026
From$160*
Seen: 6 hrs ago
One Way/Basic
Nov 2026
From$160*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $264
cmp-daily-histogram-bars-legend-max-price-aria-label $524
Displaying fares for September-2026
  • TYS–PHX, 09/22/2026: From $451
    22

    Tue

    SEP

  • TYS–PHX: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

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    24

    Thu

  • TYS–PHX, 09/25/2026: From $355
    25

    Fri

  • TYS–PHX, 09/26/2026: From $380
    26

    Sat

  • TYS–PHX: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • TYS–PHX, 09/28/2026: From $524
    28

    Mon

  • TYS–PHX, 09/29/2026: From $300
    29

    Tue

  • TYS–PHX, 09/30/2026: From $305
    30

    Wed

  • TYS–PHX, 10/01/2026: From $380
    01

    Thu

    OCT

  • TYS–PHX, 10/02/2026: From $385
    02

    Fri

  • TYS–PHX, 10/03/2026: From $340
    03

    Sat

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    04

    Sun

  • TYS–PHX, 10/05/2026: From $304
    05

    Mon

  • TYS–PHX, 10/06/2026: From $300
    06

    Tue

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    07

    Wed

  • TYS–PHX, 10/08/2026: From $304
    08

    Thu

  • TYS–PHX, 10/09/2026: From $315
    09

    Fri

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    10

    Sat

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    11

    Sun

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    12

    Mon

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    13

    Tue

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    14

    Wed

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    15

    Thu

  • TYS–PHX, 10/16/2026: From $264
    16

    Fri

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    17

    Sat

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    18

    Sun

  • TYS–PHX, 10/19/2026: From $282
    19

    Mon

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    20

    Tue

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    21

    Wed

    • Range$264-$524

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Sky Harbor International Airport
    Distance:
    1599 miles

    Route Information

    76† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 76 weekly flights from Knoxville to Phoenix on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Phoenix with Southwest, check out our Low Fare Calendar.
    You can rent a car at Sky Harbor International Airport book yours with your flight.
    Yes! Flights from Knoxville to Phoenix—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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